Evidence map›Paper›PMID 34091394›Full record

ArticleThe International journal on drug policy2021

Good Samaritan laws and overdose mortality in the United States in the fentanyl era.

Leah Hamilton, Corey S Davis, Nicole Kravitz-Wirtz, William Ponicki, Magdalena Cerdá

Open access · greenAbstract read
In one paragraph

Article in The International journal on drug policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Improving Policy Evaluations Of The Opioid Crisis.Health affairs (Project Hope) · 2025
    Article
  9. Article
  10. Article
  11. Epidemiology of 911 Calls for Opioid Overdose in Nogales, Arizona.The western journal of emergency medicine · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leah HamiltonNew York University Grossman School of Medicine, Department of Population Health, 180 Madison Avenue, 4th Floor, New York, NY 10016, United States; Kaiser Permanente Washington Health Research Institute, 1730 Minor Ave, Seattle, WA, 98101, United States. Electronic address: leah.k.hamilton@kp.org.
Corey S DavisNetwork for Public Health Law, 7101 York Avenue South, #270 Edina, MN 55435, United States.
Nicole Kravitz-WirtzUniversity of California Davis, Violence Prevention Research Program, Department of Emergency Medicine UC Davis Medical Center, 2315 Stockton Blvd., Sacramento, CA 95817, United States.
William PonickiPrevention Research Center, Pacific Institute for Research and Evaluation, 2150 Shattuck Avenue Suite 601, Berkeley, CA 94704, United States.
Magdalena CerdáNew York University Grossman School of Medicine, Department of Population Health, 180 Madison Avenue, 4th Floor, New York, NY 10016, United States.
National Health Law Program · US

Funding

Examining the Synergistic Effects of Cannabis and Prescription Opioid Policies on Chronic Pain, Opioid Prescribing, and Opioid OverdoseR01DA045872 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CERDA, MAGDALENA, MARTINS, SILVIA SABOIA · 2019 to 2023
$4.3M
NIDA NIH HHS R01 DA045872
6 · The paper itself

Abstract

backgroundAs of July 2018, 45 United States (US) states and the District of Columbia have enacted an overdose Good Samaritan law (GSL). These laws, which provide limited criminal immunity to individuals who request assistance during an overdose, may be of importance in the current wave of the overdose epidemic, which is driven primarily by illicit opioids including heroin and fentanyl. There are substantial differences in the structures of states' GSL laws which may impact their effectiveness. This study compared GSLs which have legal provisions protecting from arrest and laws which have more limited protections.

methodsUsing national county-level overdose mortality data from 3109 US counties, we examined the association of enactment of GSLs with protection from arrest and GSLs with more limited protections with subsequent overdose mortality between 2013 and 2018. Since GSLs are often enacted in conjunction with Naloxone Access Laws (NAL), we examined the effect of GSLs separately and in conjunction with NAL. We conducted these analyses using hierarchical Bayesian spatiotemporal Poisson models.

resultsGSLs with protections against arrest enactment in conjunction with a NAL were associated with 7% lower rates of all overdose deaths (rate ratio (RR): 0.93% Credible Interval (CI): 0.89-0.97), 10% lower rates in opioid overdose deaths (RR: 0.90; CI: 0.85-0.95) and 11% lower rates of heroin/synthetic overdose mortality (RR: 0.89; CI: 0.82-0.96) two years after enactment, compared to rates in states without these laws. Significant reductions in overdose mortality were not seen for GSLs with protections for charge or prosecution.

conclusionGSLs with more expansive legal protections combined with a NAL, were associated with lower rates of overdose deaths, although these risk reductions take time to manifest. Policy makers should consider enacting and implementing more expansive GSLs with arrest protections to increase the likelihood people will contact emergency services in the event of an overdose.

Indexed as

Drug OverdoseFentanylAnalgesics, OpioidBayes TheoremHumansNaloxoneUnited StatesAnalgesics, OpioidFentanylNaloxoneFentanylGood Samaritan lawsNaloxone access lawsOpioidsOverdose

Identifiers

PMID34091394
PMCPMC9529169
OpenAlexW3166544154

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.