Evidence map›Paper›PMID 34090444›Full record

ReviewMicrobial cell factories2021

Emerging prospects of macro- and microalgae as prebiotic.

Anil Kumar Patel, Reeta Rani Singhania, Mukesh Kumar Awasthi, Sunita Varjani, Shashi Kant Bhatia, Mei-Ling Tsai, Shu-Ling Hsieh, Chiu-Wen Chen, Cheng-Di Dong

Open access · goldAbstract readReview
In one paragraph

Review in Microbial cell factories, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 143 citations in OpenAlex.

  1. The Role ofNutrients · 2025
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  13. Marine drugs · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Anil Kumar Patel *Department of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, 81157, Taiwan.
Reeta Rani Singhania *Department of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, 81157, Taiwan.
Mukesh Kumar AwasthiCollege of Natural Resources and Environment, Northwest A&F University, Yangling, Shaanxi Province, 712100, People's Republic of China.
Sunita VarjaniGujarat Pollution Control Board, Gandhinagar, Gujarat, 382010, India.
Shashi Kant BhatiaDepartment of Biological Engineering, College of Engineering, Konkuk University, Seoul, 05029, Republic of Korea.
Mei-Ling TsaiDepartment of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung, 81157, Taiwan.
Shu-Ling HsiehDepartment of Seafood Science, National Kaohsiung University of Science and Technology, Kaohsiung, 81157, Taiwan.
Chiu-Wen ChenDepartment of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, 81157, Taiwan.
Cheng-Di DongDepartment of Marine Environmental Engineering, National Kaohsiung University of Science and Technology, Kaohsiung City, 81157, Taiwan. cddong@nkust.edu.tw.ORCID http://orcid.org/0000-0002-4758-3739
National Kaohsiung Marine University · TWCentral Pollution Control Board · INKonkuk University · KRNorthwest A&F University · CN

Funding

The Taiwan MOST Ref. No. 109-2222-E-992-002
6 · The paper itself

Abstract

Macro- and microalgae-based foods are becoming popular due to their high nutritious value. The algal biomass is enriched with polysaccharides, protein, polyunsaturated fatty acids, carotenoids, vitamins and minerals. However, the most promising fraction is polysaccharides (PS) or their derivatives (as dietary fibers) which are not entirely fermented by colonic bacteria hence act as potential prebiotic. Primarily, algae become famous as prominent protein sources. Recently, these are widely adopted as functional food (e.g., desserts, dairy products, oil-derivatives, pastas etc.) or animal feed (for poultry, cattle, fish etc.). Besides prebiotic and balanced amino acids source, algae derived compounds implied as therapeutics due to comprising bioactive properties to elicit immunomodulatory, antioxidative, anticancerous, anticoagulant, hepato-protective, and antihypertensive responses. Despite the above potentials, broader research determinations are inevitable to explore these algal compounds until microalgae become a business reality for broader and specific applications in all health domains. However, scale up of algal bioprocess remains a major challenge until commercial affordability is accomplished which can be possible by discovering their hidden potentials and increasing their value and application prospects. This review provides an overview of the significance of algae consumption for several health benefits in humans and animals mainly as prebiotics, however their functional food and animal feed potential are briefly covered. Moreover, their potential to develop an algal-based food industry to meet the people's requirements not only as a sustainable food solution with several health benefits but also as therapeutics is inevitable.

Indexed as

PrebioticsAnimal FeedAnimalsDietary FiberFood IndustryFunctional FoodGastrointestinal TractHumansMicroalgaePhytochemicalsPolysaccharidesSeaweedDietary FiberPhytochemicalsPolysaccharidesPrebioticsDietary fibreMacroalgaeMicroalgaePolysaccharidesPrebioticsSeaweeds

Identifiers

PMID34090444
PMCPMC8180151
OpenAlexW3168299746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.