Evidence map›Paper›PMID 34090375›Full record

ArticleBMC nephrology2021

Characteristics of ischemic stroke and intracranial hemorrhage in patients with nephrotic syndrome.

Wen-Yi Huang, Chun-Wei Chang, Chiung-Mei Chen, Kuan-Hsing Chen, Chien-Hung Chang, Hsiu-Chuan Wu, Kuo-Hsuan Chang

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wen-Yi HuangDepartment of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Keelung Branch, No.222, Mai-Jin Road, 204, Keelung, Taiwan.
Chun-Wei ChangDepartment of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Linkou Branch, 5, Fu Hsing Street, 333, Taoyuan, Taiwan.
Chiung-Mei ChenDepartment of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Linkou Branch, 5, Fu Hsing Street, 333, Taoyuan, Taiwan.
Kuan-Hsing ChenKidney Research Center, Chang Gung Memorial Hospital, Linkou Branch, Chang Gung University, School of Medicine, 5, Fu Hsing Street, Taoyuan, 333, Taiwan.
Chien-Hung ChangDepartment of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Linkou Branch, 5, Fu Hsing Street, 333, Taoyuan, Taiwan.
Hsiu-Chuan WuDepartment of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Linkou Branch, 5, Fu Hsing Street, 333, Taoyuan, Taiwan.
Kuo-Hsuan ChangDepartment of Neurology, Chang Gung University College of Medicine, Chang Gung Memorial Hospital, Linkou Branch, 5, Fu Hsing Street, 333, Taoyuan, Taiwan. gophy5128@cgmh.org.tw.
Chang Gung University · TWChang Gung Memorial Hospital · TWKeelung Chang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of cerebral stroke, including ischemic infarction and intracranial hemorrhage (ICH), increases in patients with nephrotic syndrome (NS). However, the clinical characteristics of patients with NS and stroke remain elusive. We aimed to investigate the clinical presentation and prognosis among patients with NS and ischemic stroke (IS) or ICH.

methodsWe conducted a population-based retrospective cohort study of patients with NS and acute stroke using the Chang Gung Research Database of Taiwan from January 1, 2001, to December 31, 2017. The participants were recruited from the 7 branches of Chang Gung Memorial Hospital.

resultsA total of 233 patients with IS and 57 patients with ICH were enrolled. The median age was 60 (52-70) years. The prevalence rates of hyperlipidemia, hyperuricemia, and smoking were higher in IS than in ICH. IS demonstrated lower white blood cell count (7.80 vs. 8.92 × 10

conclusionsICH demonstrated a higher risk of dependence and 30-day mortality compared with IS in patients with NS. Intensive monitoring and treatment should be applied particularly in patients with NS and ICH.

Indexed as

AgedFemaleHumansIntracranial HemorrhagesIschemic StrokeKaplan-Meier EstimateMaleMiddle AgedNephrotic SyndromeProportional Hazards ModelsRetrospective StudiesIntracerebral hemorrhageIntracranial hemorrhageIschemic strokeNephrotic syndromeStrokeSubarachnoid hemorrhage

Identifiers

PMID34090375
PMCPMC8178873
OpenAlexW3169618902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.