ArticleBMC plant biology2021
Effect of graphene / metal nanocomposites on the key genes involved in rosmarinic acid biosynthesis pathway and its accumulation in Melissa officinalis.
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 30 citations in OpenAlex.
- Exploring the influence of nanosilica on monoterpene biosynthesis, PAL1 and LS gene expression in cumin (Cuminum cyminum L.) under water-deficit stress.BMC plant biology · 2026Article
- Nano-Elicitation Approaches for Boosting Secondary Metabolites in Medicinal Plant Cell Cultures.Plants (Basel, Switzerland) · 2025Review
- Next-generation nanoformulation: Glycyrrhiza glabra-based chitosan-curcumin MgO/FeMedical oncology (Northwood, London, England) · 2025Article
- Integrative effects of phytohormones in the phenolic acids production in Salvia verticillata L. under multi-walled carbon nanotubes and methyl jasmonate elicitation.BMC plant biology · 2024Article
- Inhibitory impact of MgO nanoparticles on oxidative stress and other physiological attributes of spinach plant grown under field condition.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Application of Data Modeling, Instrument Engineering and Nanomaterials in Selected Medid the Scientific Recinal Plant Tissue Culture.Plants (Basel, Switzerland) · 2023Review
- Green synthesis of silver nanoparticles, graphene, and silver-graphene nanocomposite usingIranian journal of basic medical sciences · 2023Article
- Improving the efficiency of n-Si/PEDOT:PSS hybrid solar cells by incorporating AuNP-decorated graphene oxide as a nanoadditive for conductive polymers.RSC advances · 2022Article
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3 authors at 1 institution in 1 country.
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Abstract
backgroundRecently, numerous investigations have been done to study graphene and silver nanoparticle in the fields of agriculture and medicine. In the present study, the green synthesis of nanoparticles with two concentrations (0, 40, 60 mM) and their effect on the molecular and biochemical biosynthesis pathway of rosmarinic acid in a new method, low cost, and safe for the environment has been investigated. The transcript levels of key genes in the rosmarinic acid biosynthesis pathway (Tyrosine aminotransferase, rosmarinic acid synthase, and phenylalanine-ammonia lyase) were studied using real-time quantitative polymerase chain reaction. Then, the rosmarinic acid content was evaluated using HPLC.
resultsThe results showed that a concentration-dependent manner was observed in treated plants. At the biochemical level, the use of nanocomposites at concentration of 40 mM showed higher soluble carbohydrate (37%), flavonoids (21%), total phenol (35%) as well as total protein (47%) compared to the control plants. HPLC results showed that rosmarinic acid content in the treated plants with a low concentration of nanocomposite (40 mM) was more affected than plants treated with a high concentration of nanocomposite (60 mM) (26%) and also compared to other treatments. At the molecular level, the result showed that Tyrosine aminotransferase and rosmarinic acid synthase gene expression was positively correlated with both silver nanoparticle concentrations and nanocomposite treatments, but phenylalanine-ammonia lyase gene expression was positively correlated only with nanocomposite at 40 mM concentration. CONCLUDE: It can conclude that the nanocomposite at low concentration is more likely to induce molecular and biochemical parameters. And also, in the rosmarinic acid biosynthesis pathway, the Tyrosine aminotransferase -derived pathway is more efficient than the phenylalanine-ammonia lyase -derived pathway by causing a nano-elicitor. Therefore, it was concluded that studied elicitor at low concentration, can create plants with higher production capacity.
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