SynthesisThe journal of allergy and clinical immunology. In practice2021
Improvement in Health-Related Quality of Life in Food-Allergic Patients: A Meta-Analysis.
Synthesis in The journal of allergy and clinical immunology. In practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Systematic Review and Meta-Analysis of Oral Immunotherapy Effect on Food Allergy-Related Quality of Life.Allergy · 2025Pooled it
- Effect of oral food challenge on quality of life and family activities in children with IgE-mediated food allergies.World journal of clinical pediatrics · 2025Article
- Generic Health-Related Quality of Life of Children With Severe Peanut or Tree Nut Allergy.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Standardizing outcomes in food allergy research: aligning clinical trials with patient priorities.Current opinion in allergy and clinical immunology · 2025Review
- Food oral immunotherapy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025Review
- Key factors that influence quality of life in patients with IgE-mediated food allergy vary by age.Allergy · 2024Article
- Treatment Preferences for Acute Allergic Reactions: A Discrete Choice Experiment.Journal of health economics and outcomes research · 2024Article
- Will Oral Food Challenges Still Be Part of Allergy Care in 10 Years' Time?The journal of allergy and clinical immunology. In practice · 2023Review
- Oral Immunotherapy in Food Allergy: Where Are We Now?Allergy, asthma & immunology research · 2023Review
- Assessment of Quality of Life in Food Allergy.Allergy, asthma & immunology research · 2023Article
- Living with food allergies: the experiences of adult patients and caregivers.Frontiers in allergy · 2023Article
- Analysis of the Serum Profile of Cytokines Involved in the T-Helper Cell Type 17 Immune Response Pathway in Atopic Children with Food Allergy.International journal of environmental research and public health · 2022Article
- Low dietary adherence after a positive food challenge in food allergic adults.Clinical and translational allergy · 2022Article
- Measuring the Impact of Food Immunotherapy on Health-Related Quality of Life in Clinical Trials.Frontiers in allergy · 2022Review
- Guided Gradual Egg-Tolerance Induction in Hen's Egg Allergic Children Tolerating Baked Egg: A Prospective Randomized Trial.Frontiers in allergy · 2022Article
- Oral Immunotherapy in Children: Clinical Considerations and Practical Management.Journal of asthma and allergy · 2021Review
- Virtual Reality Reduces Pediatric Anxiety During Food Allergy Clinical Trials: A Pilot Randomized, Pragmatic Study.Frontiers in allergy · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundFood allergy (FA) is a growing global problem that can affect patients' health-related quality of life (HRQoL) owing to increased anxiety as well as social and economic restrictions. Interventions such as oral food challenges (OFCs) and oral immunotherapy (OIT) have been shown to improve HRQoL. However, meta-analyses and systematic synthesis of these data are lacking.
objectiveTo review and quantitatively synthesize potential benefits of interventions (OIT and OFC) systematically to address FA to a variety of foods.
methodsWe conducted a systematic search through PubMed and Cochrane Medical Library databases and performed a meta-analysis focusing on studies assessing changes in HRQoL after OIT and/or OFCs in FA participants and caregivers from 2010 to July 2020. Random effects model and I
resultsWe included 13 publications in this meta-analysis (OIT = 7; OFCs = 6). Mean change in HRQoL scores after OIT and OFCs was -1.25 (P < .001) and -0.78 (P = .052), with a significant I
conclusionsThis meta-analysis showed that in FA patients, both OIT and OFCs are associated with an improvement in HRQoL. Well-designed and long-term HRQoL studies are necessary to ascertain sustained benefits of OIT and OFCs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.