Evidence map›Paper›PMID 34089764›Full record

SynthesisNeuroscience and biobehavioral reviews2021

The neuroscience of social feelings: mechanisms of adaptive social functioning.

Paul J Eslinger, Silke Anders, Tommaso Ballarini, Sydney Boutros, Sören Krach, Annalina V Mayer, Jorge Moll, Tamara L Newton, Matthias L Schroeter, Ricardo de Oliveira-Souza and 5 more

Open access · hybridAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Neuroscience and biobehavioral reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
16.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.

  1. Pooled it
  2. Transforming Psychological Jurisprudence: Beyond Passivity and Determinism.Integrative psychological & behavioral science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 4 countries.

Paul J EslingerDepartments of Neurology, Neural & Behavioral Sciences, Pediatrics, and Radiology, Penn State Hershey Medical Center, Hershey, PA, USA. Electronic address: peslinger@pennstatehealth.psu.edu.
Silke AndersSocial and Affective Neuroscience, Department of Neurology, University of Lübeck, Lübeck, Germany.
Tommaso BallariniMax Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Sydney BoutrosDepartment of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, USA.
Sören KrachSocial Neuroscience Lab, Translational Psychiatry Unit, University of Lübeck, Lübeck, Germany.
Annalina V MayerSocial Neuroscience Lab, Translational Psychiatry Unit, University of Lübeck, Lübeck, Germany.
Jorge MollCognitive Neuroscience Unit, D'Or Institute for Research and Education (IDOR), Rio de Janeiro, Brazil.
Tamara L NewtonUniversity of Louisville, Department of Psychological and Brain Sciences, Louisville, KY, USA.
Matthias L SchroeterMax Planck Institute for Human Cognitive and Brain Sciences, Clinic for Cognitive Neurology, University Hospital Leipzig, Leipzig, Germany.
Ricardo de Oliveira-SouzaCognitive Neuroscience Unit, D'Or Institute for Research and Education (IDOR), BR Hospital Universitario, Universidade do Rio de Janeiro, Brazil.
Jacob RaberDepartments of Behavioral Neuroscience, Neurology, and Radiation Medicine, Division of Neuroscience, ONPRC, Oregon Health & Science University, Portland, OR, USA.
Gavin B SullivanInternational Psychoanalytic University, Berlin, Germany, Centre for Trust, Peace and Social Relations, Coventry University, UK.
James E SwainDepartment of Psychiatry and Behavioral Health, Psychology and Obstetrics and Gynecology, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.
Leroy LoweNeuroqualia (NGO), Truro, NS, Canada.
Roland ZahnCentre for Affective Disorders, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
D’Or Institute for Research and Education · BRSocial Neuroscience Lab · DEInternational Psychoanalytic University Berlin · DEKing's College London · GBMax Planck Institute for Human Cognitive and Brain Sciences · DEOregon Health & Science University · USOregon National Primate Research Center · USPenn State Milton S. Hershey Medical Center · USStony Brook School · USUniversity Hospital Leipzig · DEUniversity of Louisville · USUniversity of Lübeck · DE

Funding

Regional Brain Manganese Accumulation and Functional Consequences in WeldersR01ES019672 · NIEHS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI HUANG, XUEMEI · 2011 to 2021
$5.9M
Violence Across the Lifespan - Opioids Maternal BrainR01DA047336 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI SWAIN, JAMES EDWARD · 2019 to 2024
$3.7M
Vitamin D, Xanthohumol and Nuclear Receptors: Targeting Immunity, Microbiota andR01AT009168 · NCCIH · OREGON STATE UNIVERSITY · PI GOMBART, ADRIAN FRIEDRICH, MAIER, CLAUDIA S · 2015 to 2019
$3.0M
Effects of apoE Isoform, Sex and Diet on Insulin Regulation in BrainRF1AG059088 · NIA · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI BANKS, WILLIAM A, RABER, JACOB · 2018 to 2020
$2.5M
Guanfacine Target Engagement and Validation to Improve Substance Use Outcomes in WomenR01DA047094 · NIDA · YALE UNIVERSITY · PI SINHA, RAJITA · 2019 to 2021
$2.4M
Postpartum Intervention for Mothers with Opioid Use Disorders - Brain-Behavior MechanismsR33DA053688 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI Maria Muzik, James Edward Swain · 2025 to 2026
$1.5M
Childhood Poverty and Brain Development: The Role of Chronic Stress and ParentingRC2MD004767 · NIMHD · CORNELL UNIVERSITY · PI EVANS, GARY W, LIBERZON, ISRAEL · 2009 to 2010
$1.4M
Neuronal activity modulation and age-related neurodegenerationR21AG065914 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI DANA, HOD MICHAEL, RABER, JACOB · 2020 to 2020
$695k
Hyaluron as a regulator of chemotherapy-induced changes in neurogenesisR21CA223461 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHERMAN, LARRY S. · 2019 to 2021
$590k
Impact of Second-Hand Smoke on Brain Metabolism and Cognition in MiceR21ES027943 · NIEHS · OREGON HEALTH & SCIENCE UNIVERSITY · PI KISBY, GLEN E, RABER, JACOB · 2018 to 2019
$397k
Effects of apolipoprotein E isoform and amifostine on memory-related DNA double strand breaks and immediate-early gene expressionF31AG067629 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI BOUTROS, SYDNEY JEANNE WEBER · 2021 to 2022
$74k
NCCIH NIH HHS R01 AT009168NCI NIH HHS R21 CA223461NIA NIH HHS F31 AG067629NIA NIH HHS R21 AG065914NIA NIH HHS RF1 AG059088NIDA NIH HHS R01 DA047094NIDA NIH HHS R01 DA047336NIDA NIH HHS R33 DA053688NIEHS NIH HHS R01 ES019672NIEHS NIH HHS R21 ES027943
6 · The paper itself

Abstract

Social feelings have conceptual and empirical connections with affect and emotion. In this review, we discuss how they relate to cognition, emotion, behavior and well-being. We examine the functional neuroanatomy and neurobiology of social feelings and their role in adaptive social functioning. Existing neuroscience literature is reviewed to identify concepts, methods and challenges that might be addressed by social feelings research. Specific topic areas highlight the influence and modulation of social feelings on interpersonal affiliation, parent-child attachments, moral sentiments, interpersonal stressors, and emotional communication. Brain regions involved in social feelings were confirmed by meta-analysis using the Neurosynth platform for large-scale, automated synthesis of functional magnetic resonance imaging data. Words that relate specifically to social feelings were identfied as potential research variables. Topical inquiries into social media behaviors, loneliness, trauma, and social sensitivity, especially with recent physical distancing for guarding public and personal health, underscored the increasing importance of social feelings for affective and second person neuroscience research with implications for brain development, physical and mental health, and lifelong adaptive functioning.

Indexed as

NeurosciencesSocial InteractionCognitionEmotionsHumansSocial BehaviorEmotional communicationEmpathyInterpersonal stressorsLonelinessMoral sentimentsParent-child attachmentSecond person neuroscienceSocial affiliationSocial feelingsSocial influenceSocial mediaTrauma

Identifiers

PMID34089764
PMCPMC8388127
OpenAlexW3168018703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.