Evidence map›Paper›PMID 34089645›Full record

ArticleCurrent biology : CB2021

One-to-one innervation of vocal muscles allows precise control of birdsong.

Iris Adam, Alyssa Maxwell, Helen Rößler, Emil B Hansen, Michiel Vellema, Jonathan Brewer, Coen P H Elemans

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Transitions and tricks: nonlinear phenomena in the avian voice.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Myomatrix arrays for high-definition muscle recording.bioRxiv : the preprint server for biology · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Increasing Muscle Speed Drives Changes in the Neuromuscular Transform of Motor Commands during Postnatal Development in Songbirds.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Iris AdamDepartment of Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.
Alyssa MaxwellDepartment of Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.
Helen RößlerDepartment of Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.
Emil B HansenDepartment of Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.
Michiel VellemaDepartment of Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.
Jonathan BrewerPhyLife, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.
Coen P H ElemansDepartment of Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark. Electronic address: coen@biology.sdu.dk.
University of Southern Denmark · DK

Funding

Spike timing codes for motor controlR01NS099375 · NINDS · EMORY UNIVERSITY · PI SOBER, SAMUEL · 2017 to 2021
$1.7M
NINDS NIH HHS R01 NS099375
6 · The paper itself

Abstract

The motor control resolution of any animal behavior is limited to the minimal force step available when activating muscles, which is set by the number and size distribution of motor units (MUs) and muscle-specific force. Birdsong is an excellent model system for understanding acquisition and maintenance of complex fine motor skills, but we know surprisingly little about how the motor pool controlling the syrinx is organized and how MU recruitment drives changes in vocal output. Here we developed an experimental paradigm to measure MU size distribution using spatiotemporal imaging of intracellular calcium concentration in cross-sections of living intact syrinx muscles. We combined these measurements with muscle stress and an in vitro syrinx preparation to determine the control resolution of fundamental frequency (f

Indexed as

Nervous System Physiological PhenomenaSongbirdsAnimalsLaryngeal MusclesVocalization, Animalbirdsongmotor controlmotor unitsongbirdsound productionvocal communicationvoice

Identifiers

PMID34089645
PMCPMC8319070
OpenAlexW3168690632

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.