Evidence map›Paper›PMID 34089470›Full record

ArticleCancer causes & control : CCC2021

Differences in survival among multiple myeloma patients in the United States SEER population by neighborhood socioeconomic status and race/ethnicity.

Maira A Castañeda-Avila, Bill M Jesdale, Ariel Beccia, Ganga S Bey, Mara M Epstein

Abstract read
In one paragraph

Article in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Partnering With All Patients: Ensuring Shared Decision Making and Evidence-Based Management for Underrepresented Groups With Multiple Myeloma.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maira A Castañeda-AvilaDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, 55 Lake Road North, Worcester, MA, 01655, USA. maira.castanedaavila@umassmed.edu.ORCID http://orcid.org/0000-0002-2376-7656
Bill M JesdaleDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, 55 Lake Road North, Worcester, MA, 01655, USA.ORCID http://orcid.org/0000-0002-2697-3279
Ariel BecciaDepartment of Population and Quantitative Health Sciences, University of Massachusetts Medical School, 55 Lake Road North, Worcester, MA, 01655, USA.ORCID http://orcid.org/0000-0002-6617-7031
Ganga S BeyDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0002-9659-7096
Mara M EpsteinMeyers Primary Care Institute and the Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.ORCID http://orcid.org/0000-0001-7906-4856

Funding

University of Massachusetts Center for Clinical and Translational ScienceTL1TR001454 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEWIS, BRIAN C · 2015 to 2024
$3.6M
The Role of Monoclonal Gammopathy of Undetermined Significance Diagnosis in Healthcare UtilizationF31CA247105 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CASTANEDA-AVILA, MAIRA A · 2020 to 2020
$28k
National Cancer Institute (US) F31 CA247105-01A1National Center for Research Resources and the National Center for Advancing Translational Sciences KL2TR001454NCATS NIH HHS TL1 TR001454NCATS NIH HHS TL1TR01454NCI NIH HHS F31 CA247105
6 · The paper itself

Abstract

purposeWe examined the combined influences of race/ethnicity and neighborhood socioeconomic status (SES) on long-term survival among patients with multiple myeloma (MM).

methodsData from the 2000-2015 NCI Surveillance, Epidemiology, and End Results Program (SEER-18) were used. Census tract-level SES index was assessed in tertiles (low, medium, high SES). Competing-risk modeling was used to estimate sub-hazard ratios (SHR) and 95% confidence intervals (CIs) for SES tertile adjusted for sex and age at diagnosis and stratified by race/ethnicity.

resultsOverall, living in a low SES neighborhood was associated with worse MM survival. However, we observed some variation in the association by racial/ethnic group. Living in a low versus a high SES neighborhood was associated with a 35% (95% CI = 1.16-1.57) increase in MM-specific mortality risk among Asian/Pacific Islander cases, a 17% (95% CI = 1.12-1.22) increase among White cases, a 14% (95% CI = 1.04-1.23) increase among Black cases, and a 7% (95% CI = 0.96-1.19) increase among Hispanic cases.

conclusionThese results suggest that the influence of both SES and race/ethnicity should be considered when considering interventions to remedy disparities in MM survival.

Indexed as

EthnicityMultiple MyelomaAdolescentAdultAgedFemaleHispanic or LatinoHumansMaleMiddle AgedNative Hawaiian or Pacific IslanderSEER ProgramSocial ClassSocioeconomic FactorsUnited StatesYoung AdultMultiple myelomaRace/ethnicitySocioeconomic statusSurvival

Identifiers

PMID34089470
PMCPMC8316426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.