Evidence map›Paper›PMID 34089354›Full record

ArticleCurrent microbiology2021

Genotypical Relationship Between Human and Poultry Strains of Campylobacter jejuni.

Roberta Torres de Melo, Carolyne Ferreira Dumont, Raquelline Figueiredo Braz, Guilherme Paz Monteiro, Micaela Guidotti Takeuchi, Eduarda Cristina Alves Lourenzatto, Jandra Pacheco Dos Santos, Daise Aparecida Rossi

Abstract read
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In one paragraph

Article in Current microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Overview of Virulence and Antibiotic Resistance inAntibiotics (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Roberta Torres de MeloLaboratory of Molecular Epidemiology, Faculty of Veterinary Medicine, Federal University of Uberlândia, Ceará Street s/n, Block 2D 44, Umuarama, Uberlândia, MG, 38402-018, Brazil. roberta-melo@hotmail.com.ORCID http://orcid.org/0000-0001-8265-5163
Carolyne Ferreira DumontLaboratory of Molecular Epidemiology, Faculty of Veterinary Medicine, Federal University of Uberlândia, Ceará Street s/n, Block 2D 44, Umuarama, Uberlândia, MG, 38402-018, Brazil.
Raquelline Figueiredo BrazLaboratory of Molecular Epidemiology, Faculty of Veterinary Medicine, Federal University of Uberlândia, Ceará Street s/n, Block 2D 44, Umuarama, Uberlândia, MG, 38402-018, Brazil.
Guilherme Paz MonteiroLaboratory of Molecular Epidemiology, Faculty of Veterinary Medicine, Federal University of Uberlândia, Ceará Street s/n, Block 2D 44, Umuarama, Uberlândia, MG, 38402-018, Brazil.
Micaela Guidotti TakeuchiLaboratory of Molecular Epidemiology, Faculty of Veterinary Medicine, Federal University of Uberlândia, Ceará Street s/n, Block 2D 44, Umuarama, Uberlândia, MG, 38402-018, Brazil.
Eduarda Cristina Alves LourenzattoInstitute of Biology, Federal University of Uberlândia, Avenue Amazonas 20, Block 2D 44, Umuarama, Uberlândia, MG, 38402-018, Brazil.
Jandra Pacheco Dos SantosGoiás University Center, João Candido de Oliveira Street 115, Goiânia, GO, 74423-115, Brazil.
Daise Aparecida RossiLaboratory of Molecular Epidemiology, Faculty of Veterinary Medicine, Federal University of Uberlândia, Ceará Street s/n, Block 2D 44, Umuarama, Uberlândia, MG, 38402-018, Brazil.
Universidade Federal de Uberlândia · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 407924/2013-2Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de Minas Gerais PPM-00313-15
6 · The paper itself

Abstract

This study aimed to compare the genotype diversity of C. jejuni isolates. From the total of 64 C. jejuni strains evaluated, 44 were isolated from broiler carcasses (2015-2016) and 20 from hospitalized patients with gastroenteritis caused by the microorganism (2000-2006). The strains were correlated for the presence of flaA, pldA, cadF, ciaB, cdtABC, luxS, dnaJ, cbrA, htrA, pVir, Hcp, cstII, and neuA genes by PCR (polymerase chain reaction) and for phylogenetic proximity by PFGE (pulsed-field gel electrophoresis). Of the total strains studied, 28 (43.7%) presented all the studied genes, except pVir. Among these strains, 25 (89.3%) were of poultry origin. Poultry strains showed a higher prevalence (P < 0.05) of genes linked to adhesion, colonization, invasion, cytotoxicity, biofilm formation, and adaptation to adverse conditions. Additionally, the profile that denotes the presence of all genes identified in the study (P1) was identified in 56.8% of poultry strains and in 15.0% of human strains. Molecular typing analysis identified five pulsotypes, none of which grouped strains from different origins. Although human strains were from hospitalized patients, they presented limited virulence capacity and adaptability to adverse conditions compared to chicken carcasses, besides being different in molecular typing. However, the ability to cause Guillain-Barré Syndrome is equal for both strains. In general, poultry strains, being more recent, are more specialized to adapt to the environment, invade, and cause disease in the human host.

Indexed as

Campylobacter InfectionsCampylobacter jejuniPoultry DiseasesAnimalsChickensElectrophoresis, Gel, Pulsed-FieldHumansPhylogenyPoultryVirulence FactorsVirulence Factors

Identifiers

PMID34089354
OpenAlexW3164405745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.