Evidence map›Paper›PMID 34089346›Full record

ArticleCellular and molecular life sciences : CMLS2021

ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs.

Yevgen Zolotarov, Chao Ma, Irene González-Recio, Serge Hardy, Gijs A C Franken, Noriko Uetani, Femke Latta, Elie Kostantin, Jonathan Boulais, Marie-Pier Thibault and 7 more

Abstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. TUSC3 regulates ERMA-mediated MgNature communications · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Unlocking TRPM7 interactions: A database-driven quest.Computational and structural biotechnology journal · 2025
    Review
  8. Article
  9. Dimerization of the CNNM extracellular domain.Protein science : a publication of the Protein Society · 2024
    Article
  10. Article
  11. Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  12. Article
  13. PRL-1/2 phosphatases control TRPM7 magnesium-dependent function to regulate cellular bioenergetics.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yevgen Zolotarov *Rosalind and Morris Goodman Cancer Research Centre, McGill University, 1160 Pine Avenue W, Montréal, QC, H3A 1A3, Canada.
Chao Ma *Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands.
Irene González-RecioLiver Disease Laboratory, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160, Derio, Spain.
Serge HardyRosalind and Morris Goodman Cancer Research Centre, McGill University, 1160 Pine Avenue W, Montréal, QC, H3A 1A3, Canada.
Gijs A C FrankenDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands.
Noriko UetaniRosalind and Morris Goodman Cancer Research Centre, McGill University, 1160 Pine Avenue W, Montréal, QC, H3A 1A3, Canada.
Femke LattaDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands.
Elie KostantinRosalind and Morris Goodman Cancer Research Centre, McGill University, 1160 Pine Avenue W, Montréal, QC, H3A 1A3, Canada.
Jonathan BoulaisMontreal Clinical Research Institute (IRCM), Montréal, QC, H2W 1R7, Canada.
Marie-Pier ThibaultMontreal Clinical Research Institute (IRCM), Montréal, QC, H2W 1R7, Canada.
Jean-François CôtéMontreal Clinical Research Institute (IRCM), Montréal, QC, H2W 1R7, Canada.
Irene Díaz-MorenoInstitute for Chemical Research (IIQ), Scientific Research Centre "Isla de la Cartuja" (cicCartuja), University of Seville - CSIC, Avda. Américo Vespucio 49, 41092, Seville, Spain.
Antonio Díaz QuintanaInstitute for Chemical Research (IIQ), Scientific Research Centre "Isla de la Cartuja" (cicCartuja), University of Seville - CSIC, Avda. Américo Vespucio 49, 41092, Seville, Spain.
Joost G J HoenderopDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands.
Luis Alfonso Martínez-CruzLiver Disease Laboratory, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, 48160, Derio, Spain.
Michel L TremblayRosalind and Morris Goodman Cancer Research Centre, McGill University, 1160 Pine Avenue W, Montréal, QC, H3A 1A3, Canada. michel.tremblay@mcgill.ca.ORCID http://orcid.org/0000-0002-0281-541X
Jeroen H F de BaaijDepartment of Physiology, Radboud Institute for Molecular Life Sciences, Radboud university medical center, P.O. Box 9101, 6500HB, Nijmegen, The Netherlands. jeroen.debaaij@radboudumc.nl.

Funding

Andalusian Government BIO-198, US-1254317 and US-1257019CIHR ERT-168503CIHR MOP-142497 and FDN-159923Dutch Diabetes Research Foundation 2017.81.014European Joint Program for Rare Disease EJPRD2019-40European Union's Horizon 2020 research and innovation programme EJP RD COFUND-EJP N° 825575Fonds de Recherche du Québec - Santé #294027Fonds de Recherche du Québec - Santé PhD ScholarshipMinisterio de Ciencia, Innovación y Universidades PGC2018-096049-B-I00Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NL) NWO Veni 016.186.012. Vici 016.130.668
6 · The paper itself

Abstract

Cyclin M (CNNM1-4) proteins maintain cellular and body magnesium (Mg

Indexed as

HomeostasisADP-Ribosylation FactorsBiological TransportCyclinsGlycosylationHEK293 CellsHumansMagnesiumModels, MolecularProtein BindingADP-Ribosylation FactorsARL15 protein, humanCNNM3 protein, humanCyclinsMagnesiumCNNM2CNNM3GlycosylationMagnesium transportProtein-protein interaction

Identifiers

PMID34089346
PMCPMC8257531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.