Evidence map›Paper›PMID 34089112›Full record

ArticleBehavior genetics2021

The Analytic Identification of Variance Component Models Common to Behavior Genetics.

Michael D Hunter, S Mason Garrison, S Alexandra Burt, Joseph L Rodgers

Abstract read
In one paragraph

Article in Behavior genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  8. Effects of Genetic Relatedness of Kin Pairs on Univariate ACE Model Performance.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2023
    Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael D HunterSchool of Psychology, Georgia Institute of Technology, Atlanta, GA, 30313, USA. michael-hunter@gatech.edu.ORCID 0000-0002-3651-6709
S Mason GarrisonDepartment of Psychology, Wake Forest University, Winston-Salem, NC, 27109, USA.
S Alexandra BurtDepartment of Psychology, Michigan State University, East Lansing, MI, 48824, USA.
Joseph L RodgersDepartment of Psychology and Human Development, Vanderbilt University, Nashville, TN, 37203, USA.

Funding

Quantifying the contributions of mitochondrial DNA to Alzheimer's Disease and related conditions of agingRF1AG073189 · NIA · MICHIGAN STATE UNIVERSITY · PI BURT, S. ALEXANDRA · 2021 to 2021
$1.5M
Quantifying the contributions of mitochondrial DNA to Alzheimer's Disease and related conditions of agingR01AG073189 · NIA · MICHIGAN STATE UNIVERSITY · PI S. Alexandra Burt · 2025 to 2026
$895k
New NLSY Kinship Links and Longitudinal/Cross-Generational Models: Cognition and Fertility ResearchR01HD087395 · NICHD · VANDERBILT UNIVERSITY · PI RODGERS, JOSEPH L. · 2017 to 2019
$652k
NIA NIH HHS R01 AG073189NIA NIH HHS RF1 AG073189NICHD NIH HHS R01 HD087395
6 · The paper itself

Abstract

Many behavior genetics models follow the same general structure. We describe this general structure and analytically derive simple criteria for its identification. In particular, we find that variance components can be uniquely estimated whenever the relatedness matrices that define the components are linearly independent (i.e., not confounded). Thus, we emphasize determining which variance components can be identified given a set of genetic and environmental relationships, rather than the estimation procedures. We validate the identification criteria with several well-known models, and further apply them to several less common models. The first model distinguishes child-rearing environment from extended family environment. The second model adds a gene-by-common-environment interaction term in sets of twins reared apart and together. The third model separates measured-genomic relatedness from the scanner site variation in a hypothetical functional magnetic resonance imaging study. The computationally easy analytic identification criteria allow researchers to quickly address model identification issues and define novel variance components, facilitating the development of new research questions.

Indexed as

Models, GeneticTwinsHumansBehavior geneticsModel identificationStructural equation modelingVariance components

Identifiers

PMID34089112
PMCPMC8394168

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.