Evidence map›Paper›PMID 34089096›Full record

ArticleActa diabetologica2021

Dysglycemia after COVID-19 pneumonia: a six-month cohort study.

Chiara Molinari, Andrea Laurenzi, Amelia Caretto, Patrizia Rovere-Querini, Fabio Ciceri, Vito Lampasona, Marina Scavini, Lorenzo Piemonti

Open access · bronzeAbstract read
In one paragraph

Article in Acta diabetologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chiara MolinariSan Raffaele Diabetes Research Institute, IRCCS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy.ORCID http://orcid.org/0000-0002-2346-3759
Andrea LaurenziSan Raffaele Diabetes Research Institute, IRCCS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy.ORCID http://orcid.org/0000-0002-6073-5098
Amelia CarettoSan Raffaele Diabetes Research Institute, IRCCS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy.ORCID http://orcid.org/0000-0003-1153-6700
Patrizia Rovere-QueriniUnit of Internal Medicine and Endocrinology, IRCCS Ospedale San Raffaele, Milan, Italy.ORCID http://orcid.org/0000-0003-2615-3649
Fabio CiceriUniversità Vita-Salute San Raffaele, Milan, Italy.ORCID http://orcid.org/0000-0003-0873-0123
Vito LampasonaSan Raffaele Diabetes Research Institute, IRCCS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy.ORCID http://orcid.org/0000-0001-5162-8445
Marina ScaviniSan Raffaele Diabetes Research Institute, IRCCS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy.ORCID http://orcid.org/0000-0002-7983-6905
Lorenzo PiemontiSan Raffaele Diabetes Research Institute, IRCCS Ospedale San Raffaele, Via Olgettina 60, 20132, Milan, Italy. piemonti.lorenzo@hsr.it.ORCID http://orcid.org/0000-0002-2172-2198
IRCCS Ospedale San Raffaele · ITVita-Salute San Raffaele University · IT

Funding

IRCCS Ospedale San Raffaele Program Project COVID-19Ministero della Salute COVID-2020-12371617
6 · The paper itself

Abstract

aimThe aim of this study was to understand whether the dysglycemia associated with SARS-CoV-2 infection persists or reverts when the viral infection resolves.

methodsWe analyzed fasting blood glucose (FBG) after hospital discharge in a cohort of 621 adult cases with suspected COVID-19 pneumonia.

resultsAt admission, 18.8% of the patients in our cohort had pre-existing diabetes, 9.3% fasting glucose in the diabetes range without a prior diagnosis (DFG), 26% impaired fasting glucose (IFG), 44.9% normal fasting glucose (NFG), while 2% had no FBG available. FBG categories were similarly distributed in the 71 patients without confirmed COVID-19 pneumonia. During follow-up (median time 6 month) FBG was available for 321 out of the 453 (70.9%) surviving patients and showed a trend to a marginal increase [from 97 (87-116) to 100 (92-114) mg/dL; p = 0.071]. Transitions between FBG categories were analyzed in subjects without pre-existing diabetes (265 out of 321). We identified three groups: (i) patients who maintained or improved FBG during follow-up [Group A, n = 185; from 100 (86-109) to 94 (88-99) mg/dL; p < 0.001]; (ii) patients who moved from the NFG to IFG category [Group B, n = 66: from 89 (85-96) to 106 (102-113) mg/dl; p < 0.001]; (iii) patients who maintained or reached DFG during follow-up [Group C, n = 14: from 114 (94-138) to 134 (126-143) mg/dl; p = 0.035]. Male sex and ICU admission during the hospitalization were more prevalent in Group C compared to Group A or B.

conclusionsSix months after the SARS-CoV-2 infection DFG was evident in only few patients who experienced severe COVID-19 pneumonia.

Indexed as

COVID-19AdultBlood GlucoseCohort StudiesFastingHumansMaleRisk FactorsSARS-CoV-2Blood GlucoseCOVID-19DiabetesFasting blood glucosePneumonia

Identifiers

PMID34089096
PMCPMC8177035
OpenAlexW3162414875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.