Evidence map›Paper›PMID 34088870›Full record

ArticleMolecular cancer research : MCR2021

Mapping of m

Kellie A Cotter, John Gallon, Nadine Uebersax, Philip Rubin, Kate D Meyer, Salvatore Piscuoglio, Samie R Jaffrey, Mark A Rubin

Open access · hybridAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. The landscape of NNature genetics · 2025
    Article
  6. Review
  7. RNA NNature reviews. Urology · 2024
    Review
  8. Role of NOncology reports · 2024
    Review
  9. Article
  10. Review
  11. The mFrontiers in pharmacology · 2024
    Review
  12. Review
  13. Post-transcriptional modification of mCell death & disease · 2023
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Role of m6A writers, erasers and readers in cancer.Experimental hematology & oncology · 2022
    Review
  20. A mNAR cancer · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Kellie A CotterDepartment for BioMedical Research, University of Bern, Bern, Switzerland.ORCID 0000-0002-2574-815X
John GallonVisceral Surgery and Precision Medicine Research Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.ORCID 0000-0002-5328-6298
Nadine UebersaxDepartment for BioMedical Research, University of Bern, Bern, Switzerland.
Philip RubinDepartment for BioMedical Research, University of Bern, Bern, Switzerland.
Kate D MeyerDepartment of Biochemistry, Duke University School of Medicine, Durham, North Carolina.
Salvatore PiscuoglioVisceral Surgery and Precision Medicine Research Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.ORCID 0000-0003-2686-2939
Samie R JaffreyDepartment of Pharmacology, Weill Cornell Medicine, New York, New York. mark.rubin@dbmr.unibe.ch srj2003@med.cornell.edu.
Mark A RubinDepartment for BioMedical Research, University of Bern, Bern, Switzerland. mark.rubin@dbmr.unibe.ch srj2003@med.cornell.edu.ORCID 0000-0002-8321-9950
University of Bern · CHCornell University · USDepartment of Biomedicine Basel · CHDuke University · USUniversity Hospital of Basel · CH

Funding

Weill Cornell Medicine (WCM) SPORE in Prostate CancerP50CA211024 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LODA, MASSIMO · 2017 to 2021
$10.9M
New mechanisms and technologies for understanding post-transcriptional gene regulation in neuronsR35NS111631 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY · 2019 to 2026
$8.6M
Mechanisms of epitranscriptomic regulation in cancerR01CA186702 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY, Michael Kharas · 2014 to 2026
$8.0M
NCI NIH HHS P50 CA211024NCI NIH HHS R01 CA186702NINDS NIH HHS R35 NS111631
6 · The paper itself

Abstract

Recent evidence has highlighted the role of

Indexed as

AdenosineDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticHEK293 CellsHumansMaleMethyltransferasesProstateProstatic NeoplasmsReceptors, AndrogenReceptors, Cytoplasmic and NuclearSignal TransductionUp-RegulationAdenosineMethyltransferasesMETTL3 protein, humanReceptors, AndrogenReceptors, Cytoplasmic and Nuclear

Identifiers

PMID34088870
PMCPMC8349875
OpenAlexW3165365611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.