Trial reportProceedings of the National Academy of Sciences of the United States of America2021
Reactivation-induced motor skill learning.
Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- The use of transcranial direct current stimulation to facilitate motor skill reactivations of a choice reaction time task in adults.Physiological reports · 2025Trial
- Brain morphological changes in autism spectrum disorder related to multiple behavioral spectrums: a behavioral-causal structural covariance network analysis.European archives of psychiatry and clinical neuroscience · 2026Article
- Gradual consolidation of skilled sequential movements in primary motor cortex of non-human primates.bioRxiv : the preprint server for biology · 2026Article
- Cardiovascular exercise enhances motor learning across multiple sessions in people with Parkinson's disease: a randomized controlled pilot trial.NPJ science of learning · 2025Article
- Brief memory reactivations enable generalization of offline visual perceptual learning mechanisms.Scientific reports · 2025Article
- Training can enhance unconscious response priming on fast trials even when measuring consciousness on a trial-by-trial basis.Neuroscience of consciousness · 2025Article
- Distinct Neural Plasticity Enhancing Visual Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Procedural Motor Memory Deficits in Patients With Long-COVID.Neurology · 2024Article
- Early excitatory-inhibitory cortical modifications following skill learning are associated with motor memory consolidation and plasticity overnight.Nature communications · 2024Article
- Age-Related Differences in Motor Skill Transfer with Brief Memory Reactivation.Brain sciences · 2024Article
- Plasticity-stability dynamics during post-training processing of learning.Trends in cognitive sciences · 2024Review
- Increased cortical inhibition following brief motor memory reactivation supports reconsolidation and overnight offline learning gains.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Initial motor skill performance predicts future performance, but not learning.Scientific reports · 2023Article
- Reactivation-induced memory integration prevents proactive interference in perceptual learning.Journal of vision · 2023Article
- Reactivation-induced motor skill modulation does not operate at a rapid micro-timescale level.Scientific reports · 2023Article
- Does Motor Memory Reactivation through Practice and Post-Learning Sleep Modulate Consolidation?Clocks & sleep · 2023Article
- Brief memory reactivations induce learning in the numeric domain.NPJ science of learning · 2022Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Learning motor skills commonly requires repeated execution to achieve gains in performance. Motivated by memory reactivation frameworks predominantly originating from fear-conditioning studies in rodents, which have extended to humans, we asked the following: Could motor skill learning be achieved by brief memory reactivations? To address this question, we had participants encode a motor sequence task in an initial test session, followed by brief task reactivations of only 30 s each, conducted on separate days. Learning was evaluated in a final retest session. The results showed that these brief reactivations induced significant motor skill learning gains. Nevertheless, the efficacy of reactivations was not consistent but determined by the number of consecutive correct sequences tapped during memory reactivations. Highly continuous reactivations resulted in higher learning gains, similar to those induced by full extensive practice, while lower continuity reactivations resulted in minimal learning gains. These results were replicated in a new independent sample of subjects, suggesting that the quality of memory reactivation, reflected by its continuity, regulates the magnitude of learning gains. In addition, the change in noninvasive brain stimulation measurements of corticospinal excitability evoked by transcranial magnetic stimulation over primary motor cortex between pre- and postlearning correlated with retest and transfer performance. These results demonstrate a unique form of rapid motor skill learning and may have far-reaching implications, for example, in accelerating motor rehabilitation following neurological injuries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.