Evidence map›Paper›PMID 34088775›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Image-Guided High-Intensity Focused Ultrasound, A Novel Application for Interventional Nuclear Medicine?

Xinrui Zhang, Lisa Landgraf, Nikolaos Bailis, Michael Unger, Thies H Jochimsen, Andreas Melzer

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Xinrui ZhangInnovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Leipzig, Germany.
Lisa LandgrafInnovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Leipzig, Germany.
Nikolaos BailisDepartment of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Michael UngerInnovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Leipzig, Germany.
Thies H JochimsenDepartment of Nuclear Medicine, Leipzig University Hospital, Leipzig, Germany; and.
Andreas MelzerInnovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, Leipzig, Germany; andreas.mezler@uni-leipzig.de.
Leipzig University · DEUniversity Hospital Leipzig · DEUniversity of Dundee · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Image-guided high-intensity focused ultrasound (HIFU) has been increasingly used in medicine over the past few decades, and several systems for such have become commercially available. HIFU has passed regulatory approval around the world for the ablation of various solid tumors, the treatment of neurologic diseases, and the palliative management of bone metastases. The mechanical and thermal effects of focused ultrasound provide a possibility for histotripsy, supportive radiation therapy, and targeted drug delivery. The integration of imaging modalities into HIFU systems allows for precise temperature monitoring and accurate treatment planning, increasing the safety and efficiency of treatment. Preclinical and clinical results have demonstrated the potential of image-guided HIFU to reduce adverse effects and increase the quality of life postoperatively. Interventional nuclear image-guided HIFU is an attractive noninvasive option for the future.

Indexed as

High-Intensity Focused Ultrasound AblationNuclear MedicineAnimalsHumansNeoplasmsSurgery, Computer-Assistedhyperthermiaimage-guided HIFUPET/MR image guidancetargeted drug deliverytumor ablation

Identifiers

PMID34088775
PMCPMC8882895
OpenAlexW3165663492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.