Evidence map›Paper›PMID 34088774›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Relative Strengths of Three Linearizations of Receptor Availability: Saturation, Inhibition, and Occupancy Plots.

Javad Khodaii, Mostafa Araj-Khodaei, Manouchehr S Vafaee, Dean F Wong, Albert Gjedde

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Transient equilibrium determination of dopamine DFrontiers in nuclear medicine · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Javad KhodaiiDepartment of Mechanical Engineering, Amirkabir University of Technology, Tehran, Iran.
Mostafa Araj-KhodaeiResearch Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Manouchehr S VafaeeBRIDGE (Brain Research Inter-Disciplinary Guided Excellence), Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Dean F WongMallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri.
Albert GjeddeBRIDGE (Brain Research Inter-Disciplinary Guided Excellence), Department of Clinical Research, University of Southern Denmark, Odense, Denmark; albert.gjedde@clin.au.dk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We derived three widely used linearizations from the definition of receptor availability in molecular imaging with positron emission tomography (PET). The purpose of the present research was to determine the convergence of the results of the 3 methods in terms of 3 parameters-occupancy (s), distribution volume of the nondisplaceable reference binding compartment (V

Indexed as

BrainRadiopharmaceuticalsLinear ModelsPositron-Emission TomographyTomography, X-Ray ComputedRadiopharmaceuticalsbinding potentialinhibition plotLassen plotsPET

Identifiers

PMID34088774
PMCPMC8805780

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.