Evidence map›Paper›PMID 34088772›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

An Improved

Ronnie C Mease, Choong Mo Kang, Vivek Kumar, Sangeeta Ray Banerjee, Il Minn, Mary Brummet, Kathleen L Gabrielson, Yutian Feng, Andrew Park, Ana P Kiess and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Effective treatment of human prostate carcinoma xenografts with Single-Dose PSMA-targeted [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Review
  7. Therapeutic evaluation of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Theranostic Application of Radiohalogens in Nuclear Medicine.Nuclear medicine and molecular imaging · 2025
    Review
  9. Radionuclides Landscape in Prostate Cancer Theranostics.International journal of molecular sciences · 2025
    Review
  10. Review
  11. Review
  12. Novel astatine (European journal of nuclear medicine and molecular imaging · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. In vivo stableEJNMMI radiopharmacy and chemistry · 2024
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Ronnie C MeaseRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Choong Mo KangDepartment of Radiology, Duke University Medical Center, Durham, North Carolina.
Vivek KumarRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Sangeeta Ray BanerjeeRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Il MinnRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Mary BrummetRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Kathleen L GabrielsonDepartment of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
Yutian FengDepartment of Radiology, Duke University Medical Center, Durham, North Carolina.
Andrew ParkRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ana P KiessDepartment of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
George SgourosRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ganesan VaidyanathanDepartment of Radiology, Duke University Medical Center, Durham, North Carolina.
Michael R ZalutskyDepartment of Radiology, Duke University Medical Center, Durham, North Carolina.
Martin G PomperRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland; mpomper@jhmi.edu.
Johns Hopkins University · USDuke Medical Center · USJohns Hopkins Medicine · US

Funding

Training/Dissemination-Resource for Molecular Imaging Agents in Precision MedicineP41EB024495 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MARTIN G POMPER · 2017 to 2026
$11.8M
PSMA-based Cancer Imaging AgentsR01CA134675 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G · 2009 to 2025
$6.2M
Small Molecule PSMA-Targeted Alpha TherapyR01CA184228 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI POMPER, MARTIN G, ZALUTSKY, MICHAEL ROD · 2014 to 2023
$3.6M
NCI NIH HHS R01 CA134675NCI NIH HHS R01 CA184228NIBIB NIH HHS P41 EB024495
6 · The paper itself

Abstract

α-Particle emitters targeting the prostate-specific membrane antigen (PSMA) proved effective in treating patients with prostate cancer who were unresponsive to the corresponding β-particle therapy.

Indexed as

Glutamate Carboxypeptidase IIProstatic NeoplasmsAnimalsAntigens, SurfaceCell Line, TumorHumansLutetiumMaleMiceMice, SCIDRadiopharmaceuticalsTissue DistributionAntigens, SurfaceGlutamate Carboxypeptidase IILutetiumRadiopharmaceuticals211Atmurine modelsprostate cancerPSMAradiopharmaceutical therapyα-emitter

Identifiers

PMID34088772
PMCPMC8805774
OpenAlexW3164981285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.