Evidence map›Paper›PMID 34088750›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2021

The Association between Polluted Neighborhoods and

Loretta Erhunmwunsee, Sam E Wing, Jenny Shen, Hengrui Hu, Ernesto Sosa, Lisa N Lopez, Catherine Raquel, Melissa Sur, Pilar Ibarra-Noriega, Madeline Currey and 14 more

Abstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Secondary Lung Cancer among Survivors of Adolescent and Young Adult Cancer: A Population-Based Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  4. Article
  5. A Comparison of Neighborhood Socioeconomic Deprivation Measures and the Association with Survival among Black and White Women with Endometrial Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Loretta ErhunmwunseeDepartment of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California. LorettaE@coh.org.ORCID 0000-0002-5847-9312
Sam E WingDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.ORCID 0000-0003-4393-966X
Jenny ShenDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.ORCID 0000-0002-5742-3229
Hengrui HuDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.
Ernesto SosaDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.
Lisa N LopezDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.
Catherine RaquelDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.ORCID 0000-0001-7675-5416
Melissa SurDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.
Pilar Ibarra-NoriegaDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.ORCID 0000-0001-5292-9872
Madeline CurreyDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.
Janet LeeVital Research, Los Angeles, California.
Jae Y KimDepartment of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California.
Dan J RazDepartment of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California.
Arya AminiDepartment of Radiation Oncology, City of Hope Comprehensive Cancer Center, Duarte, California.
Sagus SampathDepartment of Radiation Oncology, City of Hope Comprehensive Cancer Center, Duarte, California.
Marianna KoczywasDepartment of Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, California.
Erminia MassarelliDepartment of Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, California.ORCID 0000-0001-7798-7286
Howard L WestDepartment of Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, California.
Karen L ReckampDepartment of Medical Oncology, Cedars-Sinai Medical Center, Los Angeles, California.ORCID 0000-0002-9213-0325
Rick A KittlesDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.ORCID 0000-0002-5004-4437
Ravi SalgiaDepartment of Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, California.
Victoria L SeewaldtDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.
Susan L NeuhausenDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.
Stacy W GrayDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California.

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
Oncology Research Career Development ProgramK12CA001727 · NCI · CITY OF HOPE NATIONAL MEDICAL CENTER · PI MORTIMER, JOANNE E. · 1992 to 2024
$14.6M
NCI NIH HHS K12 CA001727NCI NIH HHS P30 CA033572
6 · The paper itself

Abstract

backgroundPoor patients often reside in neighborhoods of lower socioeconomic status (SES) with high levels of airborne pollutants. They also have higher mortality from non-small cell lung cancer (NSCLC) than those living in wealthier communities. We investigated whether living in polluted neighborhoods is associated with somatic mutations linked with lower survival rates, i.e.,

methodsIn a retrospective cohort of 478 patients with NSCLC treated at a comprehensive cancer center between 2015 and 2018, we used logistic regression to assess associations between individual demographic and clinical characteristics, including somatic

results277 patients (58%) had somatic

conclusionsWhen controlling for individual- and neighborhood-level confounders, we find that the odds of having a IMPACT: The link between pollution and aggressive biology may contribute to the increased burden of adverse NSCLC outcomes in individuals living in lower SES neighborhoods.

Indexed as

AgedAir PollutantsCaliforniaCarcinoma, Non-Small-Cell LungFemaleHumansLung NeoplasmsMaleMutationParticulate MatterPoverty AreasResidence CharacteristicsRetrospective StudiesRisk FactorsTumor Suppressor Protein p53Air PollutantsParticulate MatterTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID34088750
PMCPMC8338883

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.