Observational studyBMJ open2021
Prospective observational cohort study on epidemiology, treatment and outcome of patients with traumatic brain injury (TBI) in German BG hospitals.
Observational study in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- [Diagnostic algorithm for the management of patients ≥ 65 years with a mild traumatic brain injury in the emergency department].Unfallchirurgie (Heidelberg, Germany) · 2026Review
- CT Imaging Patterns and Clinical Outcomes of Traumatic Brain Injury: Distribution Across Injury Mechanisms.Journal of clinical medicine · 2026Article
- Reference values for the quality of life after traumatic brain injury questionnaire and its overall scale from the adult German general population.Journal of patient-reported outcomes · 2026Article
- Functional recovery of patients with moderate and severe traumatic brain injury after extended and standard early rehabilitation.Frontiers in human neuroscience · 2026Article
- Predictors of in-hospital mortality in traumatic subarachnoid hemorrhage: a nationwide study of 67,684 patients in Germany.Brain & spine · 2026Article
- The effect of extended early rehabilitation on the treatment outcome of patients with moderate and severe traumatic brain injury.Frontiers in human neuroscience · 2025Article
- Editorial: New insights and perspectives on traumatic brain injury: integration, translation and multidisciplinary approaches.Frontiers in neurology · 2024Article
- Fuzzy C-means clustering algorithm applied in computed tomography images of patients with intracranial hemorrhage.Frontiers in neuroinformatics · 2024Article
- Classification and Characterization of Traumatic Brain Injuries in the Northern Region of Sweden.Journal of clinical medicine · 2023Article
- [Traumatic brain injury].Der Nervenarzt · 2023Article
- Omega-3 Polyunsaturated Fatty Acids Protect Neurological Function After Traumatic Brain Injury by Suppressing Microglial Transformation to the Proinflammatory Phenotype and Activating Exosomal NGF/TrkA Signaling.Molecular neurobiology · 2023Article
- Development and first results of a national databank on care and treatment outcome after traumatic brain injury.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Article
- Epidemiological and clinical characteristics predictive of ICU mortality of patients with traumatic brain injury treated at a trauma referral hospital - a cohort study.BMC neurology · 2023Article
- Long-term health-related quality of life after trauma with and without traumatic brain injury: a prospective cohort study.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
22 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSince 2000/2001, no large-scale prospective studies addressing traumatic brain injury (TBI) epidemiology in Germany have been published. Our aim was to look for a possible shift in TBI epidemiology described in other European countries, to look for possible changes in TBI management and to identify predictors of 1-year outcome especially in patients with mild TBI.
designObservational cohort study.
settingAll patients suffering from a TBI of any degree between 1 October 2014 and 30 September 2015, and who arrived in one of the seven participating BG hospitals within 24 hours after trauma, were included.
participantsIn total, 3514 patients were included. OUTCOME MEASURES: Initial care, acute hospital care and rehabilitation were documented using standardised documentation forms. A standardised telephone interview was conducted 3 and 12 months after TBI in order to obtain information on outcome.
resultsPeaks were identified in males in the early 20s and mid-50s, and in both sexes in the late 70s, with 25% of all patients aged 75 or older. A fall was the most frequent cause of TBI, followed by traffic accidents (especially bicyclists). The number of head CT scans increased, and the number of conventional X-rays of the skull decreased compared with 2000/2001. Besides, more patients were offered rehabilitation than before. Though most TBI were classified as mild, one-third of the patients participating in the telephone interview after 12 months still reported troubles attributed to TBI. Negative predictors in mild TBI were female gender, intracranial bleeding and Glasgow Coma Scale (GCS) 13/14.
conclusionThe observed epidemiologic shift in TBI (ie, elderly patients, more falls, more bicyclists) calls for targeted preventive measures. The heterogeneity behind the diagnosis 'mild TBI' emphasises the need for defining subgroups not only based on GCS.
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