Evidence map›Paper›PMID 34088552›Full record

ArticleJournal of cardiothoracic and vascular anesthesia2022

Population Characteristics and Markers for Withdrawal of Life-Sustaining Therapy in Patients on Extracorporeal Membrane Oxygenation.

Julia M Carlson, Eric W Etchill, Clare Angeli G Enriquez, Anna Peeler, Glenn J Whitman, Chun Woo Choi, Romergryko G Geocadin, Sung-Min Cho

Abstract read
In one paragraph

Article in Journal of cardiothoracic and vascular anesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia M CarlsonDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD.
Eric W EtchillDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Clare Angeli G EnriquezDepartment of Neurosciences, University of the Philippines Manila-Philippine General Hospital, Manila, Philippines.
Anna PeelerJohns Hopkins University School of Nursing, Baltimore, MD.
Glenn J WhitmanDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Chun Woo ChoiDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Romergryko G GeocadinDivision of Neuroscience Critical Care, Departments of Neurology and Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Sung-Min ChoDivision of Neuroscience Critical Care, Departments of Neurology and Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: csungmi1@jhmi.edu.

Funding

Interdisciplinary Training in Cardiovascular Health ResearchT32NR012704 · NINR · JOHNS HOPKINS UNIVERSITY · PI ALLEN, JERILYN K · 2011 to 2020
$1.8M
NINDS NIH HHS L30 NS119233NINR NIH HHS T32 NR012704
6 · The paper itself

Abstract

objectiveAs survival with extracorporeal membrane oxygenation (ECMO) therapy improves, it is important to study patients who do not survive secondary to withdrawal of life-sustaining therapy (WLST). The purpose of the present study was to determine the population and clinical characteristics of those who experienced short latency to WLST.

designRetrospective cohort study.

settingSingle academic hospital center.

participantsAdult ECMO patients.

interventionsNone. MEASUREMENTS AND MAIN

resultsDuring the study period, 150 patients (mean age 54.8 ± 15.9 y, 43.3% female) underwent ECMO (80% venoarterial ECMO and 20% venovenous ECMO). Seventy-three (48.7%) had WLST from ECMO support (median five days), and 33 of those (45.2%) had early WLST (≤five days). Patients who underwent WLST were older (60.3 ± 15.3 y v 49.6 ± 14.7 y; p < 0.001) than those who did not undergo WLST and had greater body mass index (31.7 ± 7.6 kg/m

conclusionsNearly 50% of ECMO patients underwent WLST, with approximately 25% occurring in the first 72 hours. These patients were older, sicker, and experienced a different clinical context. Unlike with other critical illnesses, neurologic injury was not a primary reason for WLST in ECMO patients.

Indexed as

Extracorporeal Membrane OxygenationAdultAgedCritical IllnessFemaleHumansMaleMiddle AgedPalliative CareRetrospective StudiesWithholding Treatmentbrain injuryextracorporeal membrane oxygenation therapywithdrawal of life-sustaining therapy

Identifiers

PMID34088552
PMCPMC9435591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.