Evidence map›Paper›PMID 34088379›Full record

ArticleJournal of cardiac failure2021

Relationships Between Objectively Measured Physical Activity, Exercise Capacity, and Quality of Life in Older Patients With Obese Heart Failure and Preserved Ejection Fraction.

Chares A German, Peter H Brubaker, M Benjamin Nelson, Jason Fanning, Fan Ye, Dalane W Kitzman

Abstract read
In one paragraph

Article in Journal of cardiac failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Daily physical activity and prognostic implications in patients with heart failure: an accelerometer study.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chares A GermanCardiology Section, Department of Internal Medicine, Wake Forest School of Medicine.
Peter H BrubakerDepartment of Health and Exercise Science. Electronic address: brubaker@wfu.edu.
M Benjamin NelsonCardiology Section, Department of Internal Medicine, Wake Forest School of Medicine.
Jason FanningDepartment of Health and Exercise Science.
Fan YeCardiology Section, Department of Internal Medicine, Wake Forest School of Medicine.
Dalane W KitzmanCardiology Section, Department of Internal Medicine, Wake Forest School of Medicine; Department of Geriatric Medicine, Sticht Center, Wake Forest University, Winston-Salem, North Carolina.

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
Exercise Intolerance in Older HFPEF PatientsR01AG018915 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2001 to 2019
$5.2M
Loss of fat tissue and functional responses to exercise in older, obese adultsR01AG020583 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI NICKLAS, BARBARA J · 2002 to 2013
$4.0M
Exercise Intolerance in Elderly Diastolic Heart FailureR37AG018915 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2005 to 2013
$3.4M
CHF TRIAL INVESTIGATING OUTCOMES OF EXERCISE TRAININGU01HL066491 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W · 2002 to 2007
$1.4M
NHLBI NIH HHS U01 HL066491NIA NIH HHS P30 AG021332NIA NIH HHS R01 AG018915NIA NIH HHS R01 AG020583NIA NIH HHS R37 AG018915
6 · The paper itself

Abstract

backgroundThe relationship between physical activity (PA), exercise capacity, and quality of life (QOL) in obese heart failure with preserved ejection fraction is poorly understood. METHODS AND

resultsThis was an ancillary study to a clinical trial. Accelerometers were used to measure light PA, moderate to vigorous PA, total PA, PA energy expenditure, and steps. Peak VO

conclusionsPA variables were modestly correlated with measures of exercise capacity and were not significantly correlated with QOL. Our findings indicate that PA, exercise capacity, and QOL assess different aspects of the patient experience in older obese patients with heart failure with preserved ejection fraction.

Indexed as

Heart FailureQuality of LifeAgedExerciseExercise ToleranceFemaleHumansMaleMiddle AgedObesityStroke Volumeexercise capacityHeart failurephysical activityquality of life

Identifiers

PMID34088379
PMCPMC8186734

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.