ArticleAntimicrobial resistance and infection control2021
The impact of the COVID-19 pandemic on healthcare-associated infections in intensive care unit patients: a retrospective cohort study.
Article in Antimicrobial resistance and infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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Who cites it
66 citing papers in PubMed.
- Prevalence and Determinants of Hospital-Acquired Infections in Intensive Care Units Before and After the COVID-19 Pandemic: A Retrospective Descriptive Surveillance Study at a Tertiary Care Hospital in Iran.Health science reports · 2026Article
- Beyond the Reported Numbers:Antibiotics (Basel, Switzerland) · 2026Article
- Increased mortality and Acinetobacter baumannii predominance despite stable healthcare-associated infection rates during the COVID-19 pandemic.BMC infectious diseases · 2026Observational
- Antimicrobial Susceptibility Patterns and Outcomes of Neonatal Early-Onset Sepsis over a Decade: Implications for Empirical Therapy in a Tertiary NICU.Journal of clinical medicine · 2026Article
- Oral Vancomycin in the Treatment ofAntibiotics (Basel, Switzerland) · 2026Article
- Healthcare-Associated Infections in Critically Ill COVID-19 Patients Across Evolving Pandemic Waves: A Retrospective ICU Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Significant Increase inGastro hep advances · 2026Article
- Beyond the Virus: The Collateral Impact of COVID-19 on Antimicrobial Consumption, Microbial Resistance, and Pharmacoeconomics.Pathogens (Basel, Switzerland) · 2025Observational
- Uncovering Gender Dimensions in Antimicrobial Resistance: A 10-Year Study of Clinical Bacterial Isolates in Uganda.Cureus · 2025Article
- Inguinal hernia repair under crisis: a retrospective cohort study of surgical outcomes across the COVID-19 era in China.Journal of minimally invasive surgery · 2025Article
- Prevalence, Microbiological Profile, and Risk Factors of Healthcare-Associated Infections in Intensive Care Units: A Retrospective Study in Aljouf, Saudi Arabia.Microorganisms · 2025Article
- Diversity versus clonality in carbapenem-resistant A. baumannii: a two-year surveillance study in four intensive care units at a large teaching hospital in Rome, Italy.Antimicrobial resistance and infection control · 2025Article
- Diabetes Mellitus and Multidrug-Resistant Gram-Negative Bacterial Infections in Critically Ill COVID-19 Patients: A Retrospective Observational Study.Diagnostics (Basel, Switzerland) · 2025Article
- Healthcare-Associated Infections: The Role of Microbial and Environmental Factors in Infection Control-A Narrative Review.Infectious diseases and therapy · 2025Review
- Trends in Healthcare-Acquired Infections Due to Multidrug-Resistant Organisms at a German University Medical Center Before and During the COVID-19 Pandemic.Microorganisms · 2025Article
- Mortality burden and epidemiology of procedure- and device-related healthcare-associated infections in the United States, 1999-2023: a CDC WONDER analysis.Frontiers in public health · 2025Article
- Infection prevention and control practices during the COVID-19 pandemic: impact on the prevalence of hospital-acquired infections in Tunisia.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Artificial intelligence in hospital infection prevention: an integrative review.Frontiers in public health · 2025Review
- Distribution of Pathogens in Early- and Late-Onset Sepsis Among Preterm Infants: A Decade-Long Study in a Tertiary Referral Neonatal Intensive Care Unit.Journal of clinical medicine · 2024Article
- Incidence and Predictors of Healthcare-Associated Infections in Patients Admitted to a Temporary Intensive Care Unit during the COVID-19 Pandemic Waves: A Two-Year (2021-2023) Retrospective Cohort Study in Rome, Italy.Antibiotics (Basel, Switzerland) · 2024Article
6 more citing papers are in PubMed but not listed here.
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring the intensive care units' (ICUs) reorganization that was forced by the COVID-19 emergency, attention to traditional infection control measures may have been reduced. Nevertheless, evidence on the effect of the COVID-19 pandemic on healthcare-associated infections (HAIs) is still limited and mixed. In this study, we estimated the pandemic impact on HAI incidence and investigated the HAI type occurring in COVID-19 patients.
methodsPatients admitted to the main ICU of the Umberto I teaching hospital of Rome from March 1st and April 4th 2020 were compared with patients hospitalized in 2019. We assessed the association of risk factors and time-to-first event through multivariable Fine and Grey's regression models, that consider the competitive risk of death on the development of HAI (Model 1) or device related-HAI (dr-HAI, Model 2) and provide estimates of the sub-distribution hazard ratio (SHR) and its associated confidence interval (CI). A subgroup analysis was performed on the 2020 cohort.
resultsData from 104 patients were retrieved. Overall, 59 HAIs were recorded, 32 of which occurred in the COVID-19 group. Patients admitted in 2020 were found to be positively associated with both HAI and dr-HAI onset (SHR: 2.66, 95% CI 1.31-5.38, and SHR: 10.0, 95% CI 1.84-54.41, respectively). Despite being not confirmed at the multivariable analysis, a greater proportion of dr-HAIs seemed to occur in COVID-19 patients, especially ventilator-associated pneumonia, and catheter-related urinary tract infections.
conclusionsWe observed an increase in the incidence of patients with HAIs, especially dr-HAIs, mainly sustained by COVID-19 patients. A greater susceptibility of these patients to device-related infections was hypothesized, but further studies are needed.
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