Evidence map›Paper›PMID 34088312›Full record

ArticleRespiratory research2021

A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS.

Lisa K Lee, Mansoureh Eghbali, Anil Sapru

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Pathobiology, Severity, and Risk Stratification of Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2023
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lisa K LeeDepartment of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine at UCLA, 757 Westwood Plaza, Suite 3325, Los Angeles, CA, 90095, USA. lklee@mednet.ucla.edu.ORCID http://orcid.org/0000-0001-5857-9260
Mansoureh EghbaliDepartment of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine at UCLA, 757 Westwood Plaza, Suite 3325, Los Angeles, CA, 90095, USA.
Anil SapruDivision of Pediatric Critical Care, Department of Pediatrics, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, MDCC 488, Los Angeles, CA, 90095, USA.
University of California, Los Angeles · US

Funding

Ancillary to ABC PICU to study MOD in critically ill childrenR01HD092471 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PINEDA SOTO, JOSE ALFREDO, SAPRU, ANIL · 2017 to 2021
$2.4M
Role of miR193 in oxidized lipid induced pulmonary hypertensionR01HL129051 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EGHBALI, MANSOUREH, REDDY, SRINIVASA T. · 2016 to 2019
$2.3M
Role of miR125 in pulmonary hypertension secondary to interstitial lung diseaseR01HL147586 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EGHBALI, MANSOUREH · 2020 to 2023
$1.9M
Coagulation and Fibrinolysis in Pediatric Insulin Titration TrialR01HL114484 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SAPRU, ANIL · 2012 to 2015
$1.6M
Targeted Genomic Analysis of Coagulation Pathways in Acute Lung InjuryK23HL085526 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SAPRU, ANIL · 2007 to 2011
$756k
National Institute of Child Health and Human Development R01HD092471-01NHLBI NIH HHS NIH K23 HL085526-01A1NHLBI NIH HHS R01 HL114484NHLBI NIH HHS R01 HL129051NHLBI NIH HHS R01 HL147586NICHD NIH HHS R01 HD092471
6 · The paper itself

Abstract

We identified a novel microRNA biomarker panel consisting of 6 microRNAs predicting mortality in pediatric acute respiratory distress syndrome patients. Each of the identified mRNA have potential mechanistic importance in acute respiratory distress syndrome and may lead to the development of pharmacologic targets.

Indexed as

BiomarkersChildChild, PreschoolFemaleHumansMaleMicroRNAsRespiratory Distress SyndromeSurvival RateBiomarkersMicroRNAsARDSBiomarkersmiRNAPediatrics

Identifiers

PMID34088312
PMCPMC8177032
OpenAlexW3165169987

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.