ArticleBMC plant biology2021
Integrated metabolome and transcriptome analysis of the anthocyanin biosynthetic pathway in relation to color mutation in miniature roses.
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 64 citations in OpenAlex.
- Temporal Partitioning of Carotenoid, Flavonoid and Anthocyanin Biosynthesis Underlies the Ontogenetic Petal Color Transition inMetabolites · 2026Article
- Functional divergence of cshalcone synthase genes RcCHS in regulating anthocyanin biosynthesis and stress responses in Rosa chinensis.Plant cell reports · 2026Article
- Metabolome and transcriptome integration provide insights into petal color variation of Chrysanthemum indicum.BMC plant biology · 2026Article
- The RcMYB308-RcEGL1 module regulates cyanidin accumulation by targeting the RcF3'H promoter in pink roses.BMC plant biology · 2026Article
- Integrated metabolome and transcriptome analysis reveals the potential mechanism of anthocyanin biosynthesis inFrontiers in plant science · 2026Article
- Integrated transcriptome and metabolome analyses provide molecular insights into the transition of flower color in the rose cultivar 'Juicy Terrazza'.BMC plant biology · 2025Article
- Identification and Expression Analysis of thePlants (Basel, Switzerland) · 2025Article
- Integrated transcriptome and metabolome analysis provides insights into anthocyanin biosynthesis in Cichorium intybus L.BMC plant biology · 2025Article
- Integrated Metabolomics and Transcriptome Analysis of Anthocyanin Biosynthetic Pathway inPlants (Basel, Switzerland) · 2025Article
- Cotyledonary somatic embryo is one kind of intermediate material similar to callus in the process of in vitro tissue culture from Rosa hybrida 'John F. Kennedy'.BMC genomics · 2024Article
- Transcriptomics and metabolomics reveal the underlying mechanism of drought treatment on anthocyanin accumulation in postharvest blood orange fruit.BMC plant biology · 2024Article
- Association Analysis of Transcriptome and Targeted Metabolites Identifies Key Genes Involved inInternational journal of molecular sciences · 2023Article
- Transcriptomic Analysis Reveals the Regulatory Mechanism of Color Diversity inPlants (Basel, Switzerland) · 2023Article
- Transcriptomic-based analysis to identify candidate genes for blue color rose breeding.Plant molecular biology · 2023Article
- Cyanidin-3-O-glucoside Contributes to Leaf Color Change by Regulating TwoInternational journal of molecular sciences · 2023Article
- Metabolic profile and transcriptome reveal the mystery of petal blotch formation in rose.BMC plant biology · 2023Article
- Transcriptomic and metabolomic data reveal key genes that are involved in the phenylpropanoid pathway and regulate the floral fragrance of Rhododendron fortunei.BMC plant biology · 2023Article
- Different color regulation mechanism in willow barks determined using integrated metabolomics and transcriptomics analyses.BMC plant biology · 2022Article
- Characterization of Anthocyanins and Their Antioxidant Activities in Indian Rose Varieties (Antioxidants (Basel, Switzerland) · 2022Article
- Transcriptome profiles of yellowish-white and fuchsia colored flowers in the Rheum palmatum complex reveal genes related to color polymorphism.Plant molecular biology · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundRoses are famous ornamental plants worldwide. Floral coloration is one of the most prominent traits in roses and is mainly regulated through the anthocyanin biosynthetic pathway. In this study, we investigated the key genes and metabolites of the anthocyanin biosynthetic pathway involved in color mutation in miniature roses. A comparative metabolome and transcriptome analysis was carried out on the Neptune King rose and its color mutant, Queen rose, at the blooming stage. Neptune King rose has light pink colored petals while Queen rose has deep pink colored petals.
resultA total of 190 flavonoid-related metabolites and 38,551 unique genes were identified. The contents of 45 flavonoid-related metabolites, and the expression of 15 genes participating in the flavonoid pathway, varied significantly between the two cultivars. Seven anthocyanins (cyanidin 3-O-glucosyl-malonylglucoside, cyanidin O-syringic acid, cyanidin 3-O-rutinoside, cyanidin 3-O-galactoside, cyanidin 3-O-glucoside, peonidin 3-O-glucoside chloride, and pelargonidin 3-O-glucoside) were found to be the major metabolites, with higher abundance in the Queen rose. Thirteen anthocyanin biosynthetic related genes showed an upregulation trend in the mutant flower, which may favor the higher levels of anthocyanins in the mutant. Besides, eight TRANSPARENT TESTA 12 genes were found upregulated in Queen rose, probably contributing to a high vacuolar sequestration of anthocyanins. Thirty transcription factors, including two MYB and one bHLH, were differentially expressed between the two cultivars.
conclusionsThis study provides important insights into major genes and metabolites of the anthocyanin biosynthetic pathway modulating flower coloration in miniature rose. The results will be conducive for manipulating the anthocyanin pathways in order to engineer novel miniature rose cultivars with specific colors.
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