Evidence map›Paper›PMID 34087874›Full record

Observational studyMedicine2021

Real-world evaluation of a computed tomography-first triage strategy for suspected Coronavirus disease 2019 in outpatients in Japan: An observational cohort study.

Shigeta Miyake, Takuma Higurashi, Takashi Jono, Taisuke Akimoto, Fumihiro Ogawa, Yasufumi Oi, Katsushi Tanaka, Yu Hara, Nobuaki Kobayashi, Hideaki Kato and 7 more

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shigeta MiyakeTeam COVID-19, Yokohama City University Hospital.
Takuma HigurashiTeam COVID-19, Yokohama City University Hospital.ORCID 0000-0002-1815-4396
Takashi JonoTeam COVID-19, Yokohama City University Hospital.
Taisuke AkimotoTeam COVID-19, Yokohama City University Hospital.
Fumihiro OgawaTeam COVID-19, Yokohama City University Hospital.
Yasufumi OiTeam COVID-19, Yokohama City University Hospital.
Katsushi TanakaTeam COVID-19, Yokohama City University Hospital.
Yu HaraTeam COVID-19, Yokohama City University Hospital.
Nobuaki KobayashiTeam COVID-19, Yokohama City University Hospital.
Hideaki KatoTeam COVID-19, Yokohama City University Hospital.
Tsuneo YamashiroDepartment of Diagnostic Radiology, Yokohama City University Graduate School of Medicine, 3-9, Fukuura, Kanazawa, Yokohama, Kanagawa.
Daisuke UtsunomiyaDepartment of Diagnostic Radiology, Yokohama City University Graduate School of Medicine, 3-9, Fukuura, Kanazawa, Yokohama, Kanagawa.
Atsushi NakajimaTeam COVID-19, Yokohama City University Hospital.
Tetsuya YamamotoTeam COVID-19, Yokohama City University Hospital.
Shin MaedaTeam COVID-19, Yokohama City University Hospital.
Takeshi KanekoTeam COVID-19, Yokohama City University Hospital.
Ichiro TakeuchiTeam COVID-19, Yokohama City University Hospital.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractThe Coronavirus disease 2019 pandemic continues to spread worldwide. Because of the absence of reliable rapid diagnostic systems, patients with symptoms of Coronavirus disease 2019 are treated as suspected of the disease. Use of computed tomography findings in Coronavirus disease 2019 are expected to be a reasonable method for triaging patients, and computed tomography-first triage strategies have been proposed. However, clinical evaluation of a computed tomography-first triage protocol is lacking.The aim of this study is to investigate the real-world efficacy and limitations of a computed tomography-first triage strategy in patients with suspected Coronavirus disease 2019.This was a single-center cohort study evaluating outpatients with fever who received medical examination at Yokohama City University Hospital, prospectively registered between 9 February and 5 May 2020. We treated according to the computed tomography-first triage protocol. The primary outcome was efficacy of the computed tomography-first triage protocol for patients with fever in an outpatient clinic. Efficacy of the computed tomography-first triage protocol for outpatients with fever was evaluated using sensitivity, specificity, positive predictive value, and negative predictive value. We conducted additional analyses of the isolation time of feverish outpatients and final diagnoses.In total, 108 consecutive outpatients with fever were examined at our hospital. Using the computed tomography-first triage protocol, 48 (44.9%) patients were classified as suspected Coronavirus disease 2019. Nine patients (18.8%) in this group were positive for severe acute respiratory syndrome coronavirus 2 using polymerase chain reaction; no patients in the group considered less likely to have Coronavirus disease 2019 tested positive for the virus. The protocol significantly shortened the duration of isolation for the not-suspected versus the suspected group (70.5 vs 1037.0 minutes, P < .001).Our computed tomography-first triage protocol was acceptable for screening patients with suspected Coronavirus disease 2019. This protocol will be helpful for appropriate triage, especially in areas where polymerase chain reaction is inadequate.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsClinical ProtocolsComorbidityCOVID-19FemaleHumansJapanMaleMiddle AgedSARS-CoV-2Sensitivity and SpecificitySeverity of Illness Index

Identifiers

PMID34087874
PMCPMC8183760

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.