Evidence map›Paper›PMID 34087217›Full record

ArticleBiophysical journal2021

Low-frequency component of photoplethysmogram reflects the autonomic control of blood pressure.

Anatoly S Karavaev, Anatoly S Borovik, Ekaterina I Borovkova, Eugeniya A Orlova, Margarita A Simonyan, Vladimir I Ponomarenko, Viktoriia V Skazkina, Vladimir I Gridnev, Boris P Bezruchko, Mikhail D Prokhorov and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

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  4. Heart rate variability in unstably housed Veterans with mental health conditions.Journal of clinical and experimental neuropsychology · 2025
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  5. A Wearable Device Towards Automatic Detection and Treatment of Opioid Overdose.IEEE transactions on biomedical circuits and systems · 2024
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  6. The connection between hypertension and diabetes and their role in heart and kidney disease development.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Anatoly S KaravaevSaratov State Medical University, Saratov, Russia; Saratov Branch of the Institute of Radio-Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia; Saratov State University, Saratov, Russia.
Anatoly S BorovikInstitute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia.
Ekaterina I BorovkovaSaratov State Medical University, Saratov, Russia; Saratov State University, Saratov, Russia.
Eugeniya A OrlovaInstitute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia.
Margarita A SimonyanSaratov State Medical University, Saratov, Russia.
Vladimir I PonomarenkoSaratov Branch of the Institute of Radio-Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia; Saratov State University, Saratov, Russia.
Viktoriia V SkazkinaSaratov State University, Saratov, Russia.
Vladimir I GridnevSaratov State Medical University, Saratov, Russia; Saratov State University, Saratov, Russia.
Boris P BezruchkoSaratov Branch of the Institute of Radio-Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia; Saratov State University, Saratov, Russia.
Mikhail D ProkhorovSaratov Branch of the Institute of Radio-Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia.
Anton R KiselevSaratov State Medical University, Saratov, Russia; National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. Electronic address: kiselev@gnicpm.ru.
Saratov State University · RUInstitute of Biomedical Problems · RUInstitute of Radio-Engineering and Electronics · RUNational Research Center for Preventive Medicine · RUSaratov State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The question of how much information the photoplethysmogram (PPG) signal contains on the autonomic regulation of blood pressure (BP) remains unsolved. This study aims to compare the low-frequency (LF) and high-frequency components of PPG and BP and assess their correlation with oscillations in interbeat (RR) intervals at similar frequencies. The PPG signal from the distal phalanx of the right index finger recorded using a reflective PPG sensor at green light, the BP signal from the left hand recorded using a Finometer, and RR intervals were analyzed. These signals were simultaneously recorded within 15 min in a supine resting condition in 17 healthy subjects (12 males and 5 females) aged 33 ± 9 years (mean ± SD). The study revealed the high coherence of LF components of PPG and BP with the LF component of RR intervals. The high-frequency components of these signals had low coherence. The analysis of the signal instantaneous phases revealed the presence of high-phase coherence between the LF components of PPG and BP. It is shown that the LF component of PPG is determined not only by local myogenic activity but also reflects the processes of autonomic control of BP.

Indexed as

PhotoplethysmographyBlood PressureFemaleHeart RateHumansMale

Identifiers

PMID34087217
PMCPMC8390904
OpenAlexW3164126098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.