Evidence map›Paper›PMID 34087177›Full record

ArticleMolecular cell2021

The GID ubiquitin ligase complex just reached the next level of complexity.

Lisa Fechtner, Thorsten Pfirrmann

Abstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lisa FechtnerInstitute of Physiological Chemistry, Martin-Luther University Halle-Wittenberg, Halle, Germany.
Thorsten PfirrmannInstitute of Physiological Chemistry, Martin-Luther University Halle-Wittenberg, Halle, Germany; Health and Medical University, Potsdam, Germany. Electronic address: thorsten.pfirrmann@health-and-medical-university.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This issue of Molecular Cell features two publications that make striking discoveries concerning the GID ubiquitin ligase complex. Kong et al. (2021) describe a substrate recognition mechanism, expanding the set of GID complex substrates, whereas Sherpa et al. (2021) unravel the molecular mechanism by which the GID complex targets the quaternary structure of a substrate.

Indexed as

Saccharomyces cerevisiae ProteinsUbiquitin-Protein LigasesSaccharomyces cerevisiaeUbiquitinSaccharomyces cerevisiae ProteinsUbiquitinUbiquitin-Protein Ligases

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.