Evidence map›Paper›PMID 34086598›Full record

ArticleGut2022

Role of the gut microbiome in mediating lactose intolerance symptoms.

M F Brandao Gois, Trishla Sinha, Johanne E Spreckels, Arnau Vich Vila, Laura A Bolte, Rinse K Weersma, Cisca Wijmenga, Jingyuan Fu, Alexandra Zhernakova, Alexander Kurilshikov

Registry-linked trialAbstract readLetterComment
In one paragraph

Article in Gut, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05668468 (Can Feeding a Bifido Bacteria That Readily Digests Lactose and Galactooligosacharides Improve Lactose Digestion and Tolerance Through Alteration of the Microbiome?), which is not on this map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05668468 naunknown statusnot on this map

Can Feeding a Bifido Bacteria That Readily Digests Lactose and Galactooligosacharides Improve Lactose Digestion and Tolerance Through Alteration of the Microbiome?

TypeinterventionalSponsorPurdue UniversityRan2022 to 2024Enrolled35ConditionsLactose IntoleranceArmsBifidobacterium adolescentis IVS-1 capsule, Placebo cellulose capsule
3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Diarrhea Caused by High-Fat and High-Protein Diet Was Associated With Intestinal Lactase-Producing Bacteria.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
  16. Review
  17. Review
  18. Genetics of irritable bowel syndrome: shifting gear via biobank-scale studies.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

M F Brandao GoisDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.ORCID 0000-0001-7918-2481
Trishla SinhaDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.
Johanne E SpreckelsDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.ORCID 0000-0002-8711-1736
Arnau Vich VilaDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.ORCID 0000-0003-4691-5583
Laura A BolteDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.ORCID 0000-0001-6036-0831
Rinse K WeersmaDepartment of Gastroenterology and Hepatology, University Medical Centre Groningen, Groningen, The Netherlands.ORCID 0000-0001-7928-7371
Cisca WijmengaDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.
Jingyuan FuDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.
Alexandra ZhernakovaDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.
Alexander KurilshikovDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands a.m.kurilshchikov@umcg.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal MicrobiomeLactose IntoleranceHumansbacterial interactionsbifidobacteriadietlactasemalabsorption

Identifiers

PMID34086598
PMCPMC8666824

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.