Evidence map›Paper›PMID 34086258›Full record

ReviewCurrent environmental health reports2021

Fine-Scale Air Pollution Models for Epidemiologic Research: Insights From Approaches Developed in the Multi-ethnic Study of Atherosclerosis and Air Pollution (MESA Air).

Kipruto Kirwa, Adam A Szpiro, Lianne Sheppard, Paul D Sampson, Meng Wang, Joshua P Keller, Michael T Young, Sun-Young Kim, Timothy V Larson, Joel D Kaufman

Registry-linked trialAbstract readReview
In one paragraph

Review in Current environmental health reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06464042 (Influence of Air Quality on the Development and Progression of Premature Coronary Artery Disease), which is not on this map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06464042 unknown statusnot on this mapstarted 2024, after this paper: background citation

Influence of Air Quality on the Development and Progression of Premature Coronary Artery Disease

TypeobservationalSponsorpablo Juan-SalvadoresRan2024 to 2025Enrolled4,272ConditionsCoronary Artery Disease Premature, Angina, Stable, Acute Coronary Syndrome, MINOCA
3 · Its place in the literature

Who cites it

89 citing papers in PubMed.

  1. Trial
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  7. Pre- and postnatal exposure to PMEnvironmental research · 2026
    Article
  8. Article
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  10. Observational
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  14. Article
  15. Article
  16. Article
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kipruto KirwaDepartment of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Seattle, WA, USA. kirwa@uw.edu.
Adam A SzpiroDepartment of Biostatistics, University of Washington School of Public Health, Seattle, WA, USA.
Lianne SheppardDepartments of Biostatistics and Environmental and Occupational Health Sciences, University of Washington School of Public Health, Seattle, WA, USA.
Paul D SampsonDepartment of Statistics, University of Washington School of Public Health, Seattle, WA, USA.
Meng WangDepartment of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Seattle, WA, USA.
Joshua P KellerDepartment of Statistics, Colorado State University, Fort Collins, CO, USA.
Michael T YoungDepartment of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Seattle, WA, USA.
Sun-Young KimDepartment of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Seattle, WA, USA.
Timothy V LarsonDepartment of Civil and Environmental Engineering, University of Washington, Seattle, WA, USA.
Joel D KaufmanDepartments of Environmental and Occupational Health Sciences, Epidemiology, and Medicine, University of Washington, Seattle, WA, USA.

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI ALI SHOJAIE · 1995 to 2026
$42.5M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
Urban Air Pollution and Pathological Brain Aging: A Nationwide Twin Study in MenP01AG055367 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MACK, WILLIAM J · 2018 to 2022
$11.5M
Biostatistics, Epidemiologic & Bioinformatic Training in Environmental HealthT32ES015459 · NIEHS · UNIVERSITY OF WASHINGTON · PI June T. Spector · 2009 to 2026
$10.6M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUG3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2016 to 2017
$5.1M
Air Pollution, the Aging Brain and Alzheimer's DiseaseR01ES026187 · NIEHS · UNIVERSITY OF WASHINGTON · PI LI, GAIL, SHEPPARD, ELIZABETH A LIANNE · 2016 to 2020
$3.8M
SPIROMICS - Air Pollution StudyR01ES023500 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N, KAUFMAN, JOEL DANIEL · 2014 to 2018
$3.2M
Environmental Determinants of Pathological Brain Aging in WHI Memory StudiesR01ES025888 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, JIU-CHIUAN, KAUFMAN, JOEL DANIEL · 2016 to 2020
$3.2M
Air Pollutants and Cardiovascular Risk: Investigating Thresholds with Pooled Cohorts and Electronic Health RecordsR01ES027696 · NIEHS · UNIVERSITY OF WASHINGTON · PI KAUFMAN, JOEL DANIEL, VAN DEN EEDEN, STEPHEN K. · 2017 to 2020
$2.5M
Air pollution, the social environment, and Alzheimer's disease: Risk and resilience in the Ginkgo Evaluation Memory StudyRF1AG057033 · NIA · UNIVERSITY OF WASHINGTON · PI FITZPATRICK, ANNETTE L., KAUFMAN, JOEL DANIEL · 2017 to 2017
$2.3M
Air Pollution, Heart Failure and Atrial Fibrillation in MESAR56ES026528 · NIEHS · UNIVERSITY OF WASHINGTON · PI KAUFMAN, JOEL DANIEL · 2017 to 2017
$601k
NIA NIH HHS P01 AG055367NIA NIH HHS RF1 AG057033NIEHS NIH HHS P30 ES007033NIEHS NIH HHS R01 ES023500NIEHS NIH HHS R01 ES025888NIEHS NIH HHS R01 ES026187NIEHS NIH HHS R01 ES027696NIEHS NIH HHS R56 ES026528NIEHS NIH HHS T32 ES015459NIH HHS UG3 OD023271NIH HHS UH3 OD023271
6 · The paper itself

Abstract

purpose of reviewEpidemiological studies of short- and long-term health impacts of ambient air pollutants require accurate exposure estimates. We describe the evolution in exposure assessment and assignment in air pollution epidemiology, with a focus on spatiotemporal techniques first developed to meet the needs of the Multi-ethnic Study of Atherosclerosis and Air Pollution (MESA Air). Initially designed to capture the substantial variation in pollutant levels and potential health impacts that can occur over small spatial and temporal scales in metropolitan areas, these methods have now matured to permit fine-scale exposure characterization across the contiguous USA and can be used for understanding long- and short-term health effects of exposure across the lifespan. For context, we highlight how the MESA Air models compare to other available exposure models. RECENT

findingsNewer model-based exposure assessment techniques provide predictions of pollutant concentrations with fine spatial and temporal resolution. These validated models can predict concentrations of several pollutants, including particulate matter less than 2.5 μm in diameter (PM

Indexed as

Air PollutantsAir PollutionAtherosclerosisEnvironmental ExposureEnvironmental MonitoringEpidemiologic StudiesHumansParticulate MatterAir PollutantsParticulate MatterAir pollutionEnvironmental epidemiologyExposure modelsSpatiotemporal models

Identifiers

PMID34086258
PMCPMC8278964

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.