Evidence map›Paper›PMID 34086076›Full record

ArticleCurrent microbiology2021

Insights into Antimicrobial Peptides from Limacus flavus Mucus.

Patricia Yumi Hayashida, Pedro Ismael da Silva Junior

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Patricia Yumi HayashidaLaboratory for Applied Toxinology (LETA) - Center of Toxins, Immune-Response and Cell Signaling - CeTICS/CEPID, Butantan Institute, São Paulo, Brazil.
Pedro Ismael da Silva JuniorLaboratory for Applied Toxinology (LETA) - Center of Toxins, Immune-Response and Cell Signaling - CeTICS/CEPID, Butantan Institute, São Paulo, Brazil. pisjr@butantan.gov.br.ORCID http://orcid.org/0000-0001-6619-6489
Instituto Butantan · BR

Funding

CAPES 001CNPq 472744/2012-7FAPESP/CeTICS 2013/07467-1Universidade de São Paulo 0000000406355304
6 · The paper itself

Abstract

Antimicrobial peptides have been a major research subject since the rise of antimicrobial resistance as a major public health problem. These molecules are considered a potential therapeutic source of antibiotics with broad-spectrum activity against microorganisms. Two antimicrobial peptides were isolated from the mucus of the Limacus flavus slug. The mucus was obtained by thermal shock, lyophilized and extracted with acetic acid. The supernatant was prefractionated in Sep-Pak and shortly thereafter fractionated by reverse-phase high-performance liquid chromatography. The manually obtained fractions were used in antimicrobial and cytotoxic assays and finally subjected to mass spectrometry (MS/MS). Characterization was performed by bioinformatics analysis with the tool Peaks

Indexed as

Antimicrobial Cationic PeptidesGastropodaAnimalsMicrobial Sensitivity TestsMucusPore Forming Cytotoxic ProteinsTandem Mass SpectrometryAntimicrobial Cationic PeptidesPore Forming Cytotoxic Proteins

Identifiers

PMID34086076
OpenAlexW3165146994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.