Evidence map›Paper›PMID 34085637›Full record

ArticleeLife2021

Unveiling the sensory and interneuronal pathways of the neuroendocrine connectome in

Sebastian Hückesfeld, Philipp Schlegel, Anton Miroschnikow, Andreas Schoofs, Ingo Zinke, André N Haubrich, Casey M Schneider-Mizell, James W Truman, Richard D Fetter, Albert Cardona and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  4. Octopamine receptors inFrontiers in molecular neuroscience · 2026
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  10. Synaptic connectome of a neurosecretory network in thebioRxiv : the preprint server for biology · 2024
    Article
  11. Article
  12. Mechanisms of gas sensing by internal sensory neurons inbioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. The connectome of an insect brain.Science (New York, N.Y.) · 2023
    Article
  17. Ionizing radiation alters functional neurotransmission inFrontiers in cellular neuroscience · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Sebastian HückesfeldDepartment of Molecular Brain Physiology and Behavior, LIMES Institute, University of Bonn, Bonn, Germany.ORCID 0000-0003-0236-6375
Philipp SchlegelDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-5633-1314
Anton MiroschnikowDepartment of Molecular Brain Physiology and Behavior, LIMES Institute, University of Bonn, Bonn, Germany.ORCID 0000-0002-2276-3434
Andreas SchoofsDepartment of Molecular Brain Physiology and Behavior, LIMES Institute, University of Bonn, Bonn, Germany.ORCID 0000-0001-7002-9181
Ingo ZinkeDepartment of Molecular Brain Physiology and Behavior, LIMES Institute, University of Bonn, Bonn, Germany.
André N HaubrichLife & Brain, Institute for Experimental Epileptology and Cognition Research, University of Bonn Medical Center Germany, Bonn, Germany.ORCID 0000-0001-7895-6203
Casey M Schneider-MizellJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID 0000-0001-9477-3853
James W TrumanJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID 0000-0002-9209-5435
Richard D FetterJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID 0000-0002-1558-100X
Albert CardonaJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID 0000-0003-4941-6536
Michael J PankratzDepartment of Molecular Brain Physiology and Behavior, LIMES Institute, University of Bonn, Bonn, Germany.ORCID 0000-0001-5458-6471
University of Bonn · DEHoward Hughes Medical Institute · USUniversity of Cambridge · GB

Funding

Howard Hughes Medical InstituteMedical Research Council MC_UP_1201/21Wellcome Trust 205038/Z/16/Z
6 · The paper itself

Abstract

Neuroendocrine systems in animals maintain organismal homeostasis and regulate stress response. Although a great deal of work has been done on the neuropeptides and hormones that are released and act on target organs in the periphery, the synaptic inputs onto these neuroendocrine outputs in the brain are less well understood. Here, we use the transmission electron microscopy reconstruction of a whole central nervous system in the

Indexed as

ConnectomeAnimalsAnimals, Genetically ModifiedCarbon DioxideDrosophila melanogasterDrosophila ProteinsInsect HormonesInterneuronsMicroscopy, Electron, TransmissionNeuropeptidesNeurosecretory SystemsSensory Receptor CellsSynapsesCarbon DioxideCrz protein, DrosophilaDh44 protein, DrosophilaDrosophila ProteinsInsect HormonesNeuropeptidescarbon dioxideconnectomeD. melanogasterinterneuronneuroendocrine systemneuropeptidesneurosciencesensory synapses

Identifiers

PMID34085637
PMCPMC8177888
OpenAlexW3165259148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.