ArticleCurrent microbiology2021
Biodegradation of Paracetamol by Some Gram-Positive Bacterial Isolates.
Article in Current microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Biotransformation of acetaminophen by a bacterial consortium isolated from wastewater treatment plant and household compost: metabolite profiling and kinetic insights.Antonie van Leeuwenhoek · 2026Article
- The hydrocarbon-degrading bacteria and fungi in oil contaminated soils of Kazakhstan: microbiome composition, enrichment, isolation and bioremediation potential.Environmental microbiome · 2026Article
- Benomyl modulates paracetamol bioaccumulation and endophytic microbiome diversity in zucchini.Scientific reports · 2025Article
- Advanced microbial engineering approaches for biodegradation of pharmaceutical pollutants.Biodegradation · 2025Review
- Impact of therapeutic pharmaceuticals on water bodies: diagnosis, ecological threat, and removal strategies.Water science and technology : a journal of the International Association on Water Pollution Research · 2025Article
- Demonstrated role of sulfate-reducing bacterial consortia in anaerobic paracetamol biodegradation.Biodegradation · 2025Article
- Pseudomonas sp. MSW2-Mediated Biodegradation of Pharmaceutical Micropollutants: Experimental and In Silico Investigations.Current microbiology · 2025Article
- Biodegradation of paracetamol by Amycolatopsis sp. Poz 14.BMC research notes · 2025Article
- Microbes as Resources to Remove PPCPs and Improve Water Quality.Microbial biotechnology · 2025Review
- Pharmaceutical Pollutants: Ecotoxicological Impacts and the Use of Agro-Industrial Waste for Their Removal from Aquatic Environments.Journal of xenobiotics · 2024Review
- Delineating acetaminophen biodegradation kinetics and metabolomics using bacterial community.Biodegradation · 2024Article
- Paracetamol mineralization strategy in laboratory scale using Aspergillus niger KCAC.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Acetaminophen-traces bioremediation with novel phenotypically and genotypically characterized 2 Streptomyces strains using chemo-informatics, in vivo, and in vitro experiments for cytotoxicity and biological activity.Journal, genetic engineering & biotechnology · 2023Article
- Insight into the High-Efficiency Benzo(a)pyrene Degradation Ability ofInternational journal of molecular sciences · 2023Article
- Acetaminophen Levels Found in Recycled Wastewater Alter Soil Microbial Community Structure and Functional Diversity.Microbial ecology · 2023Article
- Evaluation of the Defined Bacterial Consortium Efficacy in the Biodegradation of NSAIDs.Molecules (Basel, Switzerland) · 2023Article
- Diclofenac, ibuprofen, and paracetamol biodegradation: overconsumed non-steroidal anti-inflammatories drugs at COVID-19 pandemic.Frontiers in microbiology · 2023Review
- Isolation and Degradation Characteristics of PBAT Film Degrading Bacteria.International journal of environmental research and public health · 2022Article
- Packed-bed bioreactor-based evaluation of Paracoccus sp. APAP_BH8 potential for acetaminophen biodegradation.Journal of environmental qualityArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
Bacterial isolates with the capacity to remove paracetamol were selected from an activated sludge sample collected in an oxidation ditch of a wastewater treatment plant. Among these, twelve bacterial isolates were selected according to their capacity to grow in the presence of paracetamol. They were identified using the colony morphotype procedure and by 16S rRNA gene sequencing analysis, but only four of them showed the ability to utilise paracetamol as the sole carbon source in the presence of a nitrogen supply. Those four bacterial isolates were assigned to species of the genera Bacillus, [Brevibacterium], Corynebacterium and Enterococcus. Bacterial isolates were cultured in liquid mineral salt medium (MSM) spiked with 200 mg/L of paracetamol at 28 °C in the dark. In cultures inoculated with [Brevibacterium] frigoritolerans, Corynebacterium nuruki and Enterococcus faecium, removal of 97 ± 4%, 97 ± 6% and 86.9 ± 0.8% of paracetamol at 200 mg/L were obtained, respectively, while in the presence of a species belonging to Bacillus cereus group removal of the drug below the limits of detection was attained with evidence of mineralisation, after 144 h of incubation. During the degradation process, the metabolites 4-aminophenol, hydroquinone and 2-hexenoic acid were detected. As far as we know, these species are herein first-time described as paracetamol degraders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.