Evidence map›Paper›PMID 34085095›Full record

ArticleSurgical endoscopy2022

Potential survival benefits of open over laparoscopic radical gastrectomy for gastric cancer patients beyond three years after surgery: result from multicenter in-depth analysis based on propensity matching.

Ze-Ning Huang, YuBin Ma, Qi-Yue Chen, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Long-Long Cao and 5 more

Abstract readMulticenter Study
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Article
  7. Fewer Feedback Opportunities and Health Perception of Gastric Cancer Survivors: Opportunities for Patient Education.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ze-Ning HuangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
YuBin MaDepartment of Gastrointestinal Surgery, Qinghai University Affiliated Hospital, Xining, China.
Qi-Yue ChenDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Chao-Hui ZhengDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Ping LiDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Jian-Wei XieDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Jia-Bin WangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Jian-Xian LinDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Jun LuDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Long-Long CaoDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Mi LinDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Ru-Hong TuDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Ju-Li LinDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Hua-Long ZhengDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Chang-Ming HuangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China. hcmlr2002@163.com.ORCID 0000-0003-3370-0612

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe oncologic efficacy of laparoscopic versus open surgery for advanced distal gastric cancer (ADGC) beyond 3 years after surgery remain obscure.

methodsA total of 1256 patients with ADGC at two teaching institutions in China from April 2007 to December 2014 were enrolled. The general data of the two groups were identified to enable rigorous estimation of propensity scores. Restricted mean survival time (RMST) and Landmark analysis was used to compare survival.

resultsAfter matching 461 patients each in the open distal gastrectomy (ODG) and laparoscopic distal gastrectomy (LDG) groups, they were included into analysis. The 3- and 5-year overall survival (OS) and disease-free survival were comparable in two groups. RMST-stratified analysis showed that the 3-year RMST of ODG group was similar to that of LDG group in patients with cT4a (- 1.38 years, p = 0.163) or with cT4a and tumor size > 5 cm, whereas the 5-year RMST had significant differences between groups in cT4a patients(- 8.36 years, P = 0.005) or cT4a and tumor size > 5 cm patients(4.67 years, P = 0.042). In patients with cT4a and tumors > 5 cm, the number of peritoneal recurrences was significantly fewer in the ODG group than in the LDG group (4 vs. 17, P = 0.033), and the peritoneal recurrence time and multiple-site recurrence time were both later in the ODG group.

conclusionBy reducing recurrence, ODG achieves a better survival for GC patients with serous infiltration and tumors larger than 5 cm beyond 3 years after surgery. The present findings can serve as a reference for surgical options and the setting of follow-up time point for clinical studies.

Indexed as

LaparoscopyStomach NeoplasmsGastrectomyHumansLymph Node ExcisionPropensity ScoreRetrospective StudiesTreatment OutcomeADGCLDGMuticenterPropensity matchingSurvival benefits

Identifiers

PMID34085095
PMCPMC8758649

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.