Evidence map›Paper›PMID 34085059›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2020

Processing-Aware Real-Time Rendering for Optimized Tissue Visualization in Intraoperative 4D OCT.

Jakob Weiss, Michael Sommersperger, Ali Nasseri, Abouzar Eslami, Ulrich Eck, Nassir Navab

Open access · greenAbstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Real-time Deformation-aware Control for Autonomous Robotic Subretinal Injection under iOCT Guidance.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2025
    Article
  4. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Robotic Navigation Autonomy for Subretinal Injection via Intelligent Real-Time Virtual iOCT Volume Slicing.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jakob WeissTechnical University of Munich, Germany.ORCID 0000-0002-4058-2485
Michael SommerspergerTechnical University of Munich, Germany.
Ali NasseriKlinikum Rechts der Isar, Augenklinik, Munich, Germany.
Abouzar EslamiCarl Zeiss Meditec AG, Munich, Germany.
Ulrich EckTechnical University of Munich, Germany.
Nassir NavabTechnical University of Munich, Germany.
Johns Hopkins University · USTechnical University of Munich · DECarl Zeiss (Germany) · DETUM Klinikum · DE

Funding

Enabling technology for image-guided robot-assisted sub-retinal injectionsR01EB025883 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI IORDACHITA, IULIAN IOAN · 2019 to 2021
$1.5M
NIBIB NIH HHS R01 EB025883
6 · The paper itself

Abstract

Intraoperative Optical Coherence Tomography (iOCT) has advanced in recent years to provide real-time high resolution volumetric imaging for ophthalmic surgery. It enables real-time 3D feedback during precise surgical maneuvers. Intraoperative 4D OCT generally exhibits lower signal-to-noise ratio compared to diagnostic OCT and visualization is complicated by instrument shadows occluding retinal tissue. Additional constraints of processing data rates upwards of 6GB/s create unique challenges for advanced visualization of 4D OCT. Prior approaches for real-time 4D iOCT rendering have been limited to applying simple denoising filters and colorization to improve visualization. We present a novel real-time rendering pipeline that provides enhanced intraoperative visualization and is specifically designed for the high data rates of 4D iOCT. We decompose the volume into a static part consisting of the retinal tissue and a dynamic part including the instrument. Aligning the static parts over time allows temporal compounding of these structures for improved image quality. We employ a translational motion model and use axial projection images to reduce the dimensionality of the alignment. A model-based instrument segmentation on the projections discriminates static from dynamic parts and is used to exclude instruments from the compounding. Our real-time rendering method combines the compounded static information with the latest iOCT data to provide a visualization which compensates instrument shadows and improves instrument visibility. We evaluate the individual parts of our pipeline on pre-recorded OCT volumes and demonstrate the effectiveness of our method on a recorded volume sequence with a moving retinal forceps.

Indexed as

Advanced Intraoperative VisualizationOptical Coherence TomographyReal-Time Volumetric Processing

Identifiers

PMID34085059
PMCPMC8171113
OpenAlexW3090886921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.