Evidence map›Paper›PMID 34085035›Full record

ArticleOSA continuum2020

Noise and bias in optical coherence tomography intensity signal decorrelation.

Néstor Uribe-Patarroyo, Anouk L Post, Sebastián Ruiz-Lopera, Dirk J Faber, Brett E Bouma

Abstract read
In one paragraph

Article in OSA continuum, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Strip-Scanning for Efficient Widefield Retinal OCTA Mosaicking.Translational vision science & technology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Optical Imaging of Cilia in the Head and Neck.Journal of clinical medicine · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Néstor Uribe-PatarroyoWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, MA 02114, USA.ORCID 0000-0001-9201-2196
Anouk L PostAmsterdam UMC, University of Amsterdam, Department of Biomedical Engineering and Physics, Cancer Center Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Sebastián Ruiz-LoperaApplied Optics Group, Universidad EAFIT, Carrera 49 # 7 Sur-50, Medellín, Colombia.
Dirk J FaberAmsterdam UMC, University of Amsterdam, Department of Biomedical Engineering and Physics, Cancer Center Amsterdam, Amsterdam Cardiovascular Sciences, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Brett E BoumaWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, MA 02114, USA.

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Brett E Bouma · 2012 to 2026
$22.4M
Blood flow-based guidance and diagnostics using OCTK25EB024595 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI URIBE-PATARROYO, NESTOR · 2017 to 2021
$825k
NIBIB NIH HHS K25 EB024595NIBIB NIH HHS P41 EB015903
6 · The paper itself

Abstract

Functional optical coherence tomography (OCT) imaging based on the decorrelation of the intensity signal has been used extensively in angiography and is finding use in flowmetry and therapy monitoring. In this work, we present a rigorous analysis of the autocorrelation function, introduce the concepts of contrast bias, statistical bias and variability, and identify the optimal definition of the second-order autocorrelation function (ACF)

Identifiers

PMID34085035
PMCPMC8171193

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.