Evidence map›Paper›PMID 34084873›Full record

ArticleCurrent opinion in behavioral sciences2021

Mindful Positive Emotion Regulation as a Treatment for Addiction: From Hedonic Pleasure to Self-Transcendent Meaning.

Eric L Garland

Abstract read
In one paragraph

Article in Current opinion in behavioral sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Eric L GarlandCenter on Mindfulness and Integrative Health Intervention Development, University of Utah, USA.

Funding

Translational Neuropsychopharmacology Research of Nicotine AddictionR01DA038700 · NIDA · UNIVERSITY OF MISSOURI-COLUMBIA · PI FROELIGER, BRETT, GRAY, KEVIN M · 2015 to 2019
$2.9M
Targeting Hedonic Dysregulation to Address Chronic Pain and Opioid Misuse in Primary Care.R01DA042033 · NIDA · UNIVERSITY OF UTAH · PI GARLAND, ERIC LEE · 2016 to 2020
$2.8M
Neural mechanisms mediating appetitive regulation and smoking in nicotine addictionR01DA048094 · NIDA · UNIVERSITY OF MISSOURI-COLUMBIA · PI FROELIGER, BRETT, GARLAND, ERIC LEE · 2019 to 2023
$2.2M
Effects of Mindfulness-Oriented Intervention on Endogenous Opioid Mechanisms of Hedonic Regulation in Chronic Pain.R61AT009296 · NCCIH · UNIVERSITY OF UTAH · PI GARLAND, ERIC LEE, ZUBIETA, JON-KAR · 2016 to 2017
$831k
NCCIH NIH HHS R61 AT009296NIDA NIH HHS R01 DA038700NIDA NIH HHS R01 DA042033NIDA NIH HHS R01 DA048094
6 · The paper itself

Abstract

Chronic drug use is theorized to induce cortico-striatal neuroplasticity, driving an allostatic process marked by increased sensitivity to drug-related cues and decreased sensitivity to natural rewards that results in anhedonia and a dearth of positive affect. As such, positive emotion regulation represents a key mechanistic target for addictions treatment. This paper provides a conceptual model detailing how mindfulness may synergize a range of positive affective mechanisms to reduce addictive behavior, from savoring the hedonic pleasure derived from natural rewards, to self-generating interoceptive reward responses, and ultimately to cultivating self-transcendent meaning. These therapeutic processes may restructure reward processing from over-valuation of drug-related rewards back to valuation of natural rewards, and hypothetically, "reset" the default mode network dysfunction that undergirds addiction.

Indexed as

hedonicMindfulness-Oriented Recovery Enhancementopioidpositive affectrewardsavoring

Identifiers

PMID34084873
PMCPMC8168946

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.