Evidence map›Paper›PMID 34084784›Full record

ArticleERJ open research2021

A randomised study of comfort during bronchoscopy comparing conscious sedation and anaesthetist-controlled general anaesthesia, including the utility of bispectral index monitoring.

Thomas R Skinner, Joseph Churton, Timothy P Edwards, Farzad Bashirzadeh, Christopher Zappala, Justin T Hundloe, Hau Tan, Andrew J Pattison, Maryann Todman, Gunter F Hartel and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06848738 (Improving Genomic Profiling and Reducing Time to Non-small Cell Lung Cancer or Lymphoma Treatment Via Targeted Use of Endoscopic Ultrasound), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06848738 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Improving Genomic Profiling and Reducing Time to Non-small Cell Lung Cancer or Lymphoma Treatment Via Targeted Use of Endoscopic Ultrasound: a Randomized Clinical Trial on the Diagnostic Accuracy of Tissue Sampling With FNA Versus FNB

TypeinterventionalSponsorZealand University HospitalRan2024 to 2026Enrolled362ConditionsLung Cancer, Lymphoma, SarcoidosisArmsFNB, FNA
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Thomas R SkinnerDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.ORCID https://orcid.org/0000-0002-7171-1040
Joseph ChurtonDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
Timothy P EdwardsDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
Farzad BashirzadehDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
Christopher ZappalaDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
Justin T HundloeDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
Hau TanDept of Anaesthetic Services, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
Andrew J PattisonDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
Maryann TodmanDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.
Gunter F HartelStatistics Unit, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.ORCID https://orcid.org/0000-0002-5454-6450
David I FieldingDept of Thoracic Medicine, Royal Brisbane and Women's Hospital, Herston, QLD, Australia.ORCID https://orcid.org/0000-0003-2311-4919
Royal Brisbane and Women's Hospital · AUQIMR Berghofer Medical Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe difference in patient comfort with conscious sedation

methods96 subjects were randomised to receive conscious sedation or general anaesthesia for bronchoscopy. The primary outcome was subject comfort. Secondary outcomes included willingness to undergo a repeat procedure if necessary and level of sedation assessed clinically and by bispectral index (BIS) monitoring.

resultsThere was no significant difference between subject comfort scores (difference -0.01, 95% CI -0.63-0.61 on a 10-point scale; p=0.97) or willingness to undergo a repeat procedure (97.7%

conclusionConscious sedation is not inferior to general anaesthesia in providing patient comfort during bronchoscopy, despite lighter sedation, and is associated with fewer complications and comparable diagnostic accuracy. BIS monitoring may have a role in preventing complications associated with deeper sedation.

Identifiers

PMID34084784
PMCPMC8165373
OpenAlexW3145884900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.