Evidence map›Paper›PMID 34084766›Full record

ArticleFrontiers in chemistry2021

Bioactive α-Pyrone Derivatives from the Endophytic Fungus

Hong Pu, Jianxin Liu, Yeji Wang, Yuhui Peng, Wanying Zheng, Yang Tang, Boping Hui, Chunmei Nie, Xueshuang Huang, Yanwen Duan and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Rapid Discovery of Antifungal α-Pyrone Analogs fromJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Bioactive α-Pyrone Analogs from the Endophytic FungusMolecules (Basel, Switzerland) · 2024
    Article
  3. Natural resorcylic lactones derived from alternariol.Beilstein journal of organic chemistry · 2024
    Review
  4. Potential of Secondary Metabolites ofJournal of fungi (Basel, Switzerland) · 2023
    Review
  5. Chemical Investigation of EndophyticJournal of fungi (Basel, Switzerland) · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Hong PuXiangya International Academy of Translational Medicine, Central South University, Changsha, China.
Jianxin LiuSchool of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, China.
Yeji WangXiangya International Academy of Translational Medicine, Central South University, Changsha, China.
Yuhui PengSchool of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, China.
Wanying ZhengSchool of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, China.
Yang TangSchool of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, China.
Boping HuiSchool of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, China.
Chunmei NieSchool of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, China.
Xueshuang HuangHunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, Hunan University of Medicine, Huaihua, China.
Yanwen DuanXiangya International Academy of Translational Medicine, Central South University, Changsha, China.
Yong HuangXiangya International Academy of Translational Medicine, Central South University, Changsha, China.
Hunan University · CNCentral South University · CNHunan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially used in many indications, such as rheumatoid arthritis, pain, and neurodegeration. In the current study, five new compounds, including a dibenzo-α- pyrone derivative ellagic acid B (

Indexed as

anti-inflammationDiaporthe sp.endophytic fungusinducible nitric oxide synthaseNOα-pyrone

Identifiers

PMID34084766
PMCPMC8167431
OpenAlexW3163944623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.