Evidence map›Paper›PMID 34084701›Full record

ArticleJournal of bone and joint infection2021

Coagulation disorders during treatment with cefazolin and rifampicin: rare but dangerous.

Ines Kouki, Clémence Montagner, Wladimir Mauhin, Jonathan London, Thierry Lazard, Sylvie Grimbert, Valérie Zeller, Olivier Lidove

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of bone and joint infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Cefazolin-induced coagulopathy: a case report.Journal of medical case reports · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ines KoukiService de Médecine Interne, Groupe Hospitalier Diaconesses - Croix Saint-Simon, 125 rue d'Avron, 75020, Paris, France.
Clémence MontagnerService de Médecine Interne, Groupe Hospitalier Diaconesses - Croix Saint-Simon, 125 rue d'Avron, 75020, Paris, France.
Wladimir MauhinService de Médecine Interne, Groupe Hospitalier Diaconesses - Croix Saint-Simon, 125 rue d'Avron, 75020, Paris, France.
Jonathan LondonService de Médecine Interne, Groupe Hospitalier Diaconesses - Croix Saint-Simon, 125 rue d'Avron, 75020, Paris, France.
Thierry LazardService de Réanimation, Groupe Hospitalier Diaconesses - Croix Saint-Simon, 125 rue d'Avron, 75020, Paris, France.
Sylvie GrimbertService de Gastro-entérologie et Endoscopies Digestives, Groupe Hospitalier Diaconesses - Croix Saint-Simon, 125 rue d'Avron, 75020, Paris, France.
Valérie ZellerCentre de Référence des Infections Ostéo-articulaires, Groupe Hospitalier Diaconesses - Croix Saint-Simon, 125 rue d'Avron, 75020, Paris, France.
Olivier LidoveService de Médecine Interne, Groupe Hospitalier Diaconesses - Croix Saint-Simon, 125 rue d'Avron, 75020, Paris, France.
Groupe Hospitalier Diaconesses Croix Saint-Simon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a 79-year-old man with spondylodiscitis and unknown pathogen, treated with cefazolin and rifampicin. He developed a massive digestive hemorrhage. Prothrombin time was prolonged with severe vitamin-K-dependent clotting-factor deficiency. Severe bleeding can occur during cefazolin and rifampicin use. This deficiency should be assessed before prescribing cefazolin-rifampicin and prothrombin time monitored.

Identifiers

PMID34084701
PMCPMC8131959
OpenAlexW3145432660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.