ReviewAmerican journal of cardiovascular disease2021
Coronary microvascular dysfunction in Takotsubo syndrome: cause or consequence.
Review in American journal of cardiovascular disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- Coronary Microvascular Dysfunction in Stress Cardiomyopathy: At the Heart of the Problem.Life (Basel, Switzerland) · 2026Review
- Quantitative rest and stress perfusion in acute and recovery takotsubo syndrome-new physiological insights from cardiac magnetic resonance.European heart journal. Cardiovascular Imaging · 2026Article
- The Coronary Artery Changes and Complications Caused by Takotsubo Syndrome: A Review With Novel Observations.Reviews in cardiovascular medicine · 2025Review
- Multimodality Imaging in the Diagnosis of Coronary Microvascular Disease: An Update.Journal of personalized medicine · 2025Review
- Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-2: Specific Entities, Risk Stratification and Challenges After Recovery)Balkan medical journal · 2024Article
- Imaging Early Life Cardiovascular Phenotype.Circulation research · 2023Review
- Successful treatment of a severe Takotsubo syndrome case complicated by liver abscess.BMC cardiovascular disorders · 2023Article
- Article
- Critical role of the coronary microvasculature in heart disease: From pathologic driving force to "innocent" bystander.American heart journal plus : cardiology research and practice · 2022Article
- Pathophysiology of Cardiac Injury in COVID-19 Patients with Acute Ischaemic Stroke: What Do We Know So Far?-A Review of the Current Literature.Life (Basel, Switzerland) · 2022Review
- Guillain-Barré Syndrome Presenting With New-Onset Heart Failure.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Takotsubo syndrome (TS) is an acute cardiac disease entity, characterized by a transient myocardial stunning in a distinctive predominantly regional circumferential pattern. One of the discussed pathological mechanisms of TS is coronary ischemia including coronary microvascular dysfunction (CMVD). Many studies have revealed invasive or non-invasive signs of CMVD in patients with TS, and therefore some investigators believe that CMVD is the primary cause of TS. Nevertheless, other studies have not shown any sign of CMVD. In addition, those studies, which have shown signs of CMVD, do not reveal such signs in all the three coronary vessel distribution; some of the patients show signs of CMVD in two or only one coronary artery territory. Moreover, signs of CMVD in TS are more prevalent and more pronounced in the left anterior descending artery (LAD) distribution. The CMVD in TS is reversible in a pattern parallel to the improvement of myocardial wall motion abnormality. In this review, substantial evidences challenging CMVD as the primary cause of TS and supporting the concept that CMVD is a secondary or epiphenomenon in TS are provided. Furthermore, convincing explanation is given for the causes of the more prevalent and the more pronounced signs of CMVD observed in the LAD distribution.
Indexed as
Identifiers
34084653PMC8166587W3165385286What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.