Evidence map›Paper›PMID 34084609›Full record

ArticleSurgical neurology international2021

Spontaneous anterior cervicothoracic spinal epidural hematoma extending to clivus in SARS-CoV-2 infection.

Gianluca Scalia, Giuseppe Emmanuele Umana, Salvatore Marrone, Francesca Graziano, Angelo Giuffrida, Giancarlo Ponzo, Massimiliano Giuffrida, Massimo Furnari, Gianluca Galvano, Santo Bonanno and 1 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Surgical neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. A case of spontaneous thoracolumbar epidural hematoma in Covid-19 pneumonia.International journal of surgery case reports · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Gianluca ScaliaDepartment of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Giuseppe Emmanuele UmanaDepartment of Neurosurgery, Cannizzaro Hospital, Trauma Center, Gamma Knife Center, Catania, Italy.
Salvatore MarroneDepartment of Experimental Biomedicine and Clinical Neurosciences, School of Medicine, Postgraduate Residency Program in Neurological Surgery, Neurosurgical Clinic, AOUP "Paolo Giaccone", Palermo, Italy.
Francesca GrazianoDepartment of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Angelo GiuffridaDepartment of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Giancarlo PonzoDepartment of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Massimiliano GiuffridaDepartment of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Massimo FurnariDepartment of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Gianluca GalvanoDepartment of Diagnostic Imaging, Interventional Radiology and Neuroradiology, Highly Specialized Hospital and of National Importance "Garibaldi", Italy.
Santo BonannoDepartment of Emergency, Acute Care and Observation Medicine, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Giovanni Federico NicolettiDepartment of Neurosurgery, Highly Specialized Hospital and of National Importance "Garibaldi", Catania, Italy.
Ospedale Garibaldi · ITStony Brook University · USNeurological Surgery · USOspedale Cannizzaro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe treatment of spontaneous spinal epidural hematomas (SSEHs), depending on the lesion size and myeloradicular involvement, can be surgical or conservative. Here, we present a 55-year-old patient who sustained a SSEH several months following a systemic SARS-CoV-2 infection. CASE DESCRIPTION: A 55-year-old immunocompromised female (i.e., history 17 years ago of Hodgkin's lymphoma, nodular sclerosis variant) recently developed a SARS-CoV-2 infection treated with nonsteroidal anti-inflammatory agents. She then reported the sudden onset of cervicodorsalgia after a slight cervical flexion/extension maneuver. The brain and cervicothoracic spine MRI studies documented a clival anterior spinal epidural hematoma with maximum spinal compression at the T1-T2 level; it also extended inferiorly to the T6 level. Two weeks later, the follow-up MRI showed a remarkable reduction in the anteroposterior diameter of the hematoma that correlated with significant neurological improvement and almost complete pain regression. She was discharged after a total 15-day hospital stay, with complete symptoms relief.

conclusionWe present a 55-year-old chronically immunocompromised (i.e., due to the history of Hodgkin's lymphoma) female who, following a SARS-CoV-2 infection, developed an anterior SSEH extending from the clivus to the T6 spinal level that spontaneously regressed without surgical intervention.

Indexed as

COVID-19EpiduralHematomaSpinalSpontaneous

Identifiers

PMID34084609
PMCPMC8168654
OpenAlexW3163495139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.