Evidence map›Paper›PMID 34084559›Full record

ArticleApplied sciences (Basel, Switzerland)2019

Toward Development of a Vocal Fold Contact Pressure Probe: Bench-Top Validation of a Dual-Sensor Probe Using Excised Human Larynx Models.

Daryush D Mehta, James B Kobler, Steven M Zeitels, Matías Zañartu, Byron D Erath, Mohsen Motie-Shirazi, Sean D Peterson, Robert H Petrillo, Robert E Hillman

Open access · goldAbstract read
In one paragraph

Article in Applied sciences (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Synthetic, self-oscillating vocal fold models for voice production researcha).The Journal of the Acoustical Society of America · 2024
    Review
  3. The influence of sensor size on experimental measurement accuracy of vocal fold contact pressure.Proceedings of meetings on acoustics. Acoustical Society of America · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Daryush D MehtaCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA.
James B KoblerCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA.
Steven M ZeitelsCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA.
Matías ZañartuDepartment of Electronic Engineering, Universidad Técnica Federico Santa María, Valparaíso 2390123, Chile.ORCID 0000-0001-5581-4392
Byron D ErathDepartment of Mechanical & Aeronautical Engineering, Clarkson University, Potsdam, NY 13699, USA.ORCID 0000-0003-0057-6731
Mohsen Motie-ShiraziDepartment of Mechanical & Aeronautical Engineering, Clarkson University, Potsdam, NY 13699, USA.
Sean D PetersonDepartment of Mechanical and Mechatronics Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada.ORCID 0000-0001-8746-2491
Robert H PetrilloCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA.
Robert E HillmanCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, MA 02114, USA.
Harvard University · USClarkson University · USFederico Santa María Technical University · CLUniversity of Waterloo · CA

Funding

Use of ambulatory biofeedback to improve behavioral treatment of vocal hyperfunctionP50DC015446 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI Robert E Hillman · 2017 to 2026
$25.5M
NIDCD NIH HHS P50 DC015446
6 · The paper itself

Abstract

A critical element in understanding voice production mechanisms is the characterization of vocal fold collision, which is widely considered a primary etiological factor in the development of common phonotraumatic lesions such as nodules and polyps. This paper describes the development of a transoral, dual-sensor intraglottal/subglottal pressure probe for the simultaneous measurement of vocal fold collision and subglottal pressures during phonation using two miniature sensors positioned 7.6 mm apart at the distal end of a rigid cannula. Proof-of-concept testing was performed using excised whole-mount and hemilarynx human tissue aerodynamically driven into self-sustained oscillation, with systematic variation of the superior-inferior positioning of the vocal fold collision sensor. In the hemilarynx experiment, signals from the pressure sensors were synchronized with an acoustic microphone, a tracheal-surface accelerometer, and two high-speed video cameras recording at 4000 frames per second for top-down and en face imaging of the superior and medial vocal fold surfaces, respectively. As expected, the intraglottal pressure signal exhibited an impulse-like peak when vocal fold contact occurred, followed by a broader peak associated with intraglottal pressure build-up during the de-contacting phase. As subglottal pressure was increased, the peak amplitude of the collision pressure increased and typically reached a value below that of the average subglottal pressure. Results provide important baseline vocal fold collision pressure data with which computational models of voice production can be developed and in vivo measurements can be referenced.

Indexed as

excised larynxhemilarynxintraglottal pressuresubglottal pressurevocal fold collision

Identifiers

PMID34084559
PMCPMC8171492
OpenAlexW2981127692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.