Evidence map›Paper›PMID 34084367›Full record

ArticleChemical science2019

Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes.

Hai-Hao Han, Adam C Sedgwick, Ying Shang, Na Li, Tingting Liu, Bo-Han Li, Kunqian Yu, Yi Zang, James T Brewster, Maria L Odyniec and 7 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Boronate ester cross-linked PVA hydrogels for the capture and HChemical communications (Cambridge, England) · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 4 countries.

Hai-Hao HanKey Laboratory for Advanced Materials, Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology 130 Meilong Road Shanghai 200237 P. R. China xphe@ecust.edu.cn.
Adam C SedgwickDepartment of Chemistry, University of Bath Bath BA2 7AY UK chstdj@bath.ac.uk.ORCID https://orcid.org/0000-0002-3132-2913
Ying ShangKey Laboratory for Advanced Materials, Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology 130 Meilong Road Shanghai 200237 P. R. China xphe@ecust.edu.cn.
Na LiNational Facility for Protein Science in Shanghai, Zhangjiang Laboratory Shanghai 201210 P. R. China.
Tingting LiuNational Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences 189 Guo Shoujing Rd. Shanghai 201203 P. R. China jli@ecust.edu.cn.
Bo-Han LiNational Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences 189 Guo Shoujing Rd. Shanghai 201203 P. R. China jli@ecust.edu.cn.
Kunqian YuNational Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences 189 Guo Shoujing Rd. Shanghai 201203 P. R. China jli@ecust.edu.cn.
Yi ZangNational Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences 189 Guo Shoujing Rd. Shanghai 201203 P. R. China jli@ecust.edu.cn.
James T BrewsterDepartment of Chemistry, University of Texas at Austin 105 E 24th Street A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu.ORCID https://orcid.org/0000-0002-4579-8074
Maria L OdyniecDepartment of Chemistry, University of Bath Bath BA2 7AY UK chstdj@bath.ac.uk.ORCID https://orcid.org/0000-0001-9501-2044
Maria WeberDepartment of Chemistry, University of Bath Bath BA2 7AY UK chstdj@bath.ac.uk.ORCID https://orcid.org/0000-0002-7492-1035
Steven D BullDepartment of Chemistry, University of Bath Bath BA2 7AY UK chstdj@bath.ac.uk.ORCID https://orcid.org/0000-0001-8244-5123
Jia LiNational Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences 189 Guo Shoujing Rd. Shanghai 201203 P. R. China jli@ecust.edu.cn.
Jonathan L SesslerDepartment of Chemistry, University of Texas at Austin 105 E 24th Street A5300 Austin TX 78712-1224 USA sessler@cm.utexas.edu.ORCID https://orcid.org/0000-0002-9576-1325
Tony D JamesDepartment of Chemistry, University of Bath Bath BA2 7AY UK chstdj@bath.ac.uk.ORCID https://orcid.org/0000-0002-4095-2191
Xiao-Peng HeKey Laboratory for Advanced Materials, Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology 130 Meilong Road Shanghai 200237 P. R. China xphe@ecust.edu.cn.
He TianKey Laboratory for Advanced Materials, Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology 130 Meilong Road Shanghai 200237 P. R. China xphe@ecust.edu.cn.
Chinese Academy of Sciences · CNUniversity of Bath · GBEast China University of Science and Technology · CNProtein Express (United States) · USShanghai University · CNThe University of Texas at Austin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report a protein-based hybridization strategy that exploits the host-guest chemistry of HSA (human serum albumin) to solubilize the otherwise cell impermeable ONOO

Identifiers

PMID34084367
PMCPMC8145178
OpenAlexW2990936145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.