ArticleChemical science2019
N-Directed fluorination of unactivated Csp
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Nonheme Mononuclear and Dinuclear Iron(II) and Iron(III) Fluoride Complexes and Their Fluorine Radical Transfer Reactivity.Inorganic chemistry · 2025Article
- Engineering non-haem iron enzymes for enantioselective C(sp3)-F bond formation via radical fluorine transfer.Nature synthesis · 2024Article
- Biocatalytic enantioselective C(spNature synthesis · 2024Article
- Benzylic C(spBeilstein journal of organic chemistry · 2024Review
- Copper-Catalyzed Electrochemical C-H Fluorination.Chem catalysis · 2023Article
- δ-C-H Halogenation Reactions Enabled by a Nitrogen-Centered Radical Precursor.Organic letters · 2022Article
- Directed evolution of nonheme iron enzymes to access abiological radical-relay C(spScience (New York, N.Y.) · 2022Article
- Directed Ni-Catalyzed Reductive Arylation of Aliphatic C-H Bonds.Organic letters · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Site-selective fluorination of aliphatic C-H bonds remains synthetically challenging. While directed C-H fluorination represents the most promising approach, the limited work conducted to date has enabled just a few functional groups as the arbiters of direction. Leveraging insights gained from both computations and experimentation, we enabled the use of the ubiquitous amine functional group as a handle for the directed C-H fluorination of Csp
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.