Evidence map›Paper›PMID 34084253›Full record

ReviewApplied physics reviews2021

Photodynamic viral inactivation: Recent advances and potential applications.

Jace A Willis, Vsevolod Cheburkanov, Giulia Kassab, Jennifer M Soares, Kate C Blanco, Vanderlei S Bagnato, Vladislav V Yakovlev

Abstract readReview
In one paragraph

Review in Applied physics reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Antimicrobial photodynamic therapy reprograms resistance by inducing sensitization in methicillin-resistant Staphylococcus aureus.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  2. Article
  3. Layer-dependent modulation ofCurrent research in microbial sciences · 2026
    Article
  4. Review
  5. Review
  6. Membrane-Targeting Antivirals.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Near-Infrared Dyes: Towards Broad-Spectrum Antivirals.International journal of molecular sciences · 2022
    Review
  16. Breaking down antibiotic resistance in methicillin-resistantProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  17. Lung surfactant negatively affects the photodynamic inactivation of bacteria-in vitro and molecular dynamic simulation analyses.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Article
  19. Review
  20. Photodynamic disinfection and its role in controlling infectious diseases.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jace A WillisDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas, USA.ORCID https://orcid.org/0000-0001-5625-4059
Vsevolod CheburkanovDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas, USA.
Giulia KassabSão Carlos Institute of Physics, University of São Paulo, São Carlos, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-9055-7763
Jennifer M SoaresSão Carlos Institute of Physics, University of São Paulo, São Carlos, São Paulo, Brazil.
Kate C BlancoSão Carlos Institute of Physics, University of São Paulo, São Carlos, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-0361-9725
Vanderlei S Bagnato
Vladislav V YakovlevDepartment of Biomedical Engineering, Texas A&M University, College Station, Texas, USA.ORCID https://orcid.org/0000-0002-4557-1013

Funding

Brillouin Microscope for Biomedical ResearchR01GM127696 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI YAKOVLEV, VLADISLAV V. · 2018 to 2021
$1.1M
Sensing local nano-environment with coherent Raman microspectroscopyR21GM142107 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI YAKOVLEV, VLADISLAV V. · 2021 to 2022
$399k
NIGMS NIH HHS R01 GM127696NIGMS NIH HHS R21 GM142107
6 · The paper itself

Abstract

Antibiotic-resistant bacteria, which are growing at a frightening rate worldwide, has put the world on a long-standing alert. The COVID-19 health crisis reinforced the pressing need to address a fast-developing pandemic. To mitigate these health emergencies and prevent economic collapse, cheap, practical, and easily applicable infection control techniques are essential worldwide. Application of light in the form of photodynamic action on microorganisms and viruses has been growing and is now successfully applied in several areas. The efficacy of this approach has been demonstrated in the fight against viruses, prompting additional efforts to advance the technique, including safety use protocols. In particular, its application to suppress respiratory tract infections and to provide decontamination of fluids, such as blood plasma and others, can become an inexpensive alternative strategy in the fight against viral and bacterial infections. Diverse early treatment methods based on photodynamic action enable an accelerated response to emerging threats prior to the availability of preventative drugs. In this review, we evaluate a vast number of photodynamic demonstrations and first-principle proofs carried out on viral control, revealing its potential and encouraging its rapid development toward safe clinical practice. This review highlights the main research trends and, as a futuristic exercise, anticipates potential situations where photodynamic treatment can provide a readily available solution.

Identifiers

PMID34084253
PMCPMC8132927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.