ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2021
Oxidant/antioxidant status in Type-2 diabetes mellitus patients with metabolic syndrome.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Trends in Total Antioxidant Status and Other Biochemical Parameters in Type 2 Diabetes Mellitus: A Case-control Study.Current diabetes reviews · 2026Observational
- Polyphenol-Rich Beverages Exert Beneficial but Variable Effects on Oxidative, and Inflammatory Markers in Metabolic Syndrome and Related Conditions: Evidence of Human Trials.Foods (Basel, Switzerland) · 2025Review
- Na+/K+-ATPase: a multifunctional target in type 2 diabetes and pancreatic islets.Frontiers in immunology · 2025Review
- Obesity Is Associated with Oxidative Stress Markers and Antioxidant Enzyme Activity in Mexican Children.Antioxidants (Basel, Switzerland) · 2024Article
- Melatonin supplementation counteracts fiber loss in knee ligaments of diabetes-induced rats.Frontiers in pharmacology · 2024Article
- Risk Estimation of Gestational Diabetes Mellitus in the First Trimester.The Journal of clinical endocrinology and metabolism · 2023Article
- Adiponectin and leptin levels of patients after sleeve gastrectomy, Roux-en-Y gastric bypass, and single anastomosis sleeve ileal bypass surgeries.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023Article
- Detrimental Effects of Lipid Peroxidation in Type 2 Diabetes: Exploring the Neutralizing Influence of Antioxidants.Antioxidants (Basel, Switzerland) · 2022Review
- Beneficial effects of MgSOMolecular biology reports · 2022Article
- Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundThe concurrence of metabolic syndrome (MS) and diabetes mellitus (DM) is increasing worldwide. The long-term complications of these chronic diseases are a threat to patients' well-being. Oxidative stress is involved in the pathogenesis of several diseases. To understand the basic pathophysiological mechanisms of Type-2 DM (T2DM) and its related complications, we aimed to investigate the oxidant/antioxidant status and Na MATERIALS AND
methodsA population of ninety individuals including fifty patients diagnosed with T2DM and MS, but without overt diabetes complications, and forty individuals without T2DM or MS as control group participated in this study. Plasma malondialdehyde (MDA), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx) activities, total antioxidant capacity (TAC), and Na
resultsPlasma MDA in patients group was statistically significantly higher than that of controls (
conclusionBecause T2DM patients were without any vascular complications, antioxidant defense results may reflect the lack of progression of diabetes complications in these patients. These results emphasize the need for initial and continued assessment of cardiovascular disease risks in diabetic individuals. Implementation of timely interventions may improve the management of diabetes and prevent the progression of diabetes complications.
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