Evidence map›Paper›PMID 34084140›Full record

ArticleFrontiers in pharmacology2021

Protective Role of

Eleonora Starikova, Jennet Mammedova, Arina Ozhiganova, Aleksandra Lebedeva, Anna Malashicheva, Daria Semenova, Evgeniia Khokhlova, Eleonora Mameli, Andrea Caporali, Jimi Wills and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Eleonora StarikovaLaboratory of Immunoregulation, Department of Immunology, Institute of Experimental Medicine, St. Petersburg, Russian Federation.
Jennet MammedovaLaboratory of General Immunology, Department of Immunology, Institute of Experimental Medicine, St. Petersburg, Russian Federation.
Arina OzhiganovaLaboratory of Immunoregulation, Department of Immunology, Institute of Experimental Medicine, St. Petersburg, Russian Federation.
Aleksandra LebedevaLaboratory of Immunoregulation, Department of Immunology, Institute of Experimental Medicine, St. Petersburg, Russian Federation.
Anna MalashichevaLaboratory of Molecular Cardiology, Almazov National Medical Research Centre, St. Petersburg, Russian Federation.
Daria SemenovaLaboratory of Molecular Cardiology, Almazov National Medical Research Centre, St. Petersburg, Russian Federation.
Evgeniia KhokhlovaLaboratory of Regenerative Biomedicine, Institute of Cytology RAS, St. Petersburg, Russian Federation.
Eleonora MameliLaboratory of Vascular Biology, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Andrea CaporaliLaboratory of Vascular Biology, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Jimi WillsCancer Research United Kingdom Edinburgh Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom.
Alexey SokolovLaboratory of Biochemical Genetics, Department of Molecular Genetics, Institute of Experimental Medicine, St. Petersburg, Russian Federation.
Institute of Experimental Medicine · RUInstitute of Cytology · RUUniversity of Edinburgh · GBEdinburgh Cancer Research · GBFederal Almazov North-West Medical Research Centre · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute liver injury in its terminal phase trigger systemic inflammatory response syndrome with multiple organ failure. An uncontrolled inflammatory reaction is difficult to treat and contributes to high mortality. Therefore, to solve this problem a search for new therapeutic approaches remains urgent. This study aimed to explore the protective effects of

Indexed as

acute liver injuryIL-6M. edulis hydrolysatenitric oxidevascular permeabilityVCAM-1

Identifiers

PMID34084140
PMCPMC8167060
OpenAlexW3161677963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.