Evidence map›Paper›PMID 34083860›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2021

Determination of the distribution of drug concentration and tissue optical properties for ALA-mediated anal photodynamic therapy.

Yi Hong Ong, Andrew C Li, Theresa M Busch, Timothy C Zhu

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. A Comparison of Two Probes to Determine Rectum Optical Properties.Proceedings of SPIE--the International Society for Optical Engineering · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yi Hong OngDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Andrew C LiDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Theresa M BuschDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Timothy C ZhuDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
California University of Pennsylvania · USUniversity of Pennsylvania · US

Funding

TUMOR HYPOXIA, PHOTOSENSITIZER, VASCULARITY AND PDTP01CA087971 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M, CENGEL, KEITH A · 2001 to 2019
$24.8M
In situ PEDSy and light delivery platform for Intracavitory Photodynamic TherapyR01EB028778 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI POTASEK, MARY, ZHU, TIMOTHY C. · 2020 to 2023
$2.2M
Treating high grade intraepithelial lesions of the anus with photodynamic therapyR21CA223366 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BEN-JOSEF, EDGAR, BUSCH, THERESA M · 2018 to 2019
$380k
NCI NIH HHS P01 CA087971NCI NIH HHS R21 CA223366NIBIB NIH HHS R01 EB028778
6 · The paper itself

Abstract

PDT efficacy depends on the availability and dynamic interactions of photosensitizer, light, and oxygen. Tissue optical properties influence the delivered light dose and impact PDT outcome.

Indexed as

analcylindrical cavityfluorescenceOptical propertiesphotodynamic therapyphotosensitizer concentrationPpIX

Identifiers

PMID34083860
PMCPMC8171263
OpenAlexW3134592188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.