Evidence map›Paper›PMID 34083859›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2021

A Comparison of Two Probes to Determine Rectum Optical Properties.

Andrew C Li, Yi Hong Ong, Celina Li, Jie He, Andreea Dimofte, Theresa M Busch, Brian C Wilson, Robert Weersink, Timothy C Zhu

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Andrew C LiDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Yi Hong OngDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Celina LiUniversity of Toronto/University Health Network, Toronto, ON M5G 2C4, Canada.
Jie HeUniversity of Toronto/University Health Network, Toronto, ON M5G 2C4, Canada.
Andreea DimofteDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Theresa M BuschDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
Brian C WilsonUniversity of Toronto/University Health Network, Toronto, ON M5G 2C4, Canada.
Robert WeersinkUniversity of Toronto/University Health Network, Toronto, ON M5G 2C4, Canada.
Timothy C ZhuDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104.
University of Toronto · CAUniversity of Pennsylvania · USCalifornia University of Pennsylvania · US

Funding

TUMOR HYPOXIA, PHOTOSENSITIZER, VASCULARITY AND PDTP01CA087971 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M, CENGEL, KEITH A · 2001 to 2019
$24.8M
In situ PEDSy and light delivery platform for Intracavitory Photodynamic TherapyR01EB028778 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI POTASEK, MARY, ZHU, TIMOTHY C. · 2020 to 2023
$2.2M
Cherenkov imaging of Total Skin Electron Therapy (TSET)R21CA239127 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ZHU, TIMOTHY C. · 2020 to 2021
$386k
Treating high grade intraepithelial lesions of the anus with photodynamic therapyR21CA223366 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BEN-JOSEF, EDGAR, BUSCH, THERESA M · 2018 to 2019
$380k
NCI NIH HHS P01 CA087971NCI NIH HHS R21 CA223366NCI NIH HHS R21 CA239127NIBIB NIH HHS R01 EB028778
6 · The paper itself

Abstract

Tissue optical properties are crucial for determining the light dose delivered to the tumor. Two probes are compared: the two-catheter probe is based on transmittance measurement between one point source and one isotropic detector inside parallel catheters spaced at 0.5 cm along a 1-inch diameter transparent cylinder; and a 1-inch trans-rectal diffuse optical tomography (DOT) probe designed for prostate measurements, using a multiple fiber-array with source-detector separations of 1.4-10 mm. The two-catheter probe uses an empirical model for primary and scatter light fluence rates in the cylindrical cavity condition for anal PDT to determine optical properties along the source catheter using dual motors to move the source and detector along the catheters. The DOT probe uses finite element method (FEM) to obtain distribution of optical properties in 3D. Validations for the two probes were performed in liquid and solid phantoms. For each method, validation was performed in tissue-mimicking liquid phantoms for a range of known optical properties (μ

Indexed as

diffuse optical tomographylight fluence rateRectal optical propertiesspectroscopytissue-mimicking phantoms

Identifiers

PMID34083859
PMCPMC8171236
OpenAlexW3134383337

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.