Evidence map›Paper›PMID 34083857›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2021

Cherenkov imaging for Total Skin Electron Therapy - an evaluation of dose uniformity.

Timothy C Zhu, Yihong Ong, Hongjin Sun, Weili Zhong, Tianshun Miao, Andreea Dimofte, Petr Bruza, Amit Maity, John P Plastaras, Ima Paydar and 2 more

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Imaging and characterization of optical emission fromPhysics in medicine and biology · 2024
    Article
  6. Article
  7. Total Skin Treatment with Helical Arc Radiotherapy.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Timothy C ZhuDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Yihong OngDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Hongjin SunDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Weili ZhongDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Tianshun MiaoThayer School of Engineering, Dartmouth College, Hanover, NH 03755.
Andreea DimofteDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Petr BruzaThayer School of Engineering, Dartmouth College, Hanover, NH 03755.
Amit MaityDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
John P PlastarasDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Ima PaydarDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Lei DongDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, NH 03755.

Funding

Cherenkov imaging of Total Skin Electron Therapy (TSET)R21CA239127 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ZHU, TIMOTHY C. · 2020 to 2021
$386k
NCI NIH HHS R21 CA239127
6 · The paper itself

Abstract

Total Skin Electron Therapy (TSET) utilizes high-energy electrons to treat cancers on the entire body surface. The otherwise invisible radiation beam can be observed via the optical Cherenkov photons emitted from interaction between the high-energy electron beam and tissue. Cherenkov emission can be used to evaluate the dose uniformity on the surface of the patient in real-time using a time-gated intensified camera system. Each patient was monitored during TSET by in-vivo detectors (IVD) as well as Scintillators. Patients undergoing TSET in various conditions (whole body and half body) were imaged and analyzed. A rigorous methodology for converting Cherenkov intensity to surface dose as products of correction factors, including camera vignette correction factor, incident radiation correction factor, and tissue optical properties correction factor. A comprehensive study has been carried out by inspecting various positions on the patients such as vertex, chest, perineum, shins, and foot relative to the umbilicus point (the prescription point).

Indexed as

biomedical opticsCherenkov imagingRadiation TherapyTotal Skin Electron Therapy

Identifiers

PMID34083857
PMCPMC8171222

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.